Qa-1b Modulates Resistance to Anti-PD-1 Immune Checkpoint Blockade in Tumors with Defects in Antigen Processing

Immune checkpoint blockade (ICB) has improved cancer care, but ICB is only effective in some patients. The molecular mechanisms that influence ICB therapy response are not completely understood. The non-classical MHC class I molecule HLA-E and its mouse ortholog, Qa-1b, present a limited set of pept...

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Bibliographic Details
Published in:	Molecular cancer research Vol. 19; no. 6; p. 1076
Main Authors:	Zhang, Xiao, Sabio, Erich, Krishna, Chirag, Ma, Xiaoxiao, Wang, Jingming, Jiang, Hui, Havel, Jonathan J, Chan, Timothy A
Format:	Journal Article
Language:	English
Published:	01.06.2021
ISSN:	1557-3125, 1557-3125
Online Access:	Get more information
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