StarCDP: Dynamic Programming Algorithms for Fast and Accurate Cell Lineage Tree Reconstruction from CRISPR-Based Lineage Tracing Data

CRISPR-based lineage tracing, coupled with single-cell RNA sequencing, has emerged as a promising approach for studying development and disease progression at the cellular level. Thus, cell lineage tree (CLT) reconstruction has attracted significant attention in recent years, including the introduct...

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Bibliographic Details
Published in:Journal of computational biology
Main Authors: Dai, Junyan, Molloy, Erin K
Format: Journal Article
Language:English
Published: United States 23.10.2025
Subjects:
CRISPR
phylogenetics
Camin-Sokal
lineage tracing
parsimony
star homoplasy
ISSN:1557-8666, 1557-8666
Online Access:Get more information
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