Magnetic resonance imaging in the diagnosis of non-tumorous multifocal brain lesions mimicking multiple sclerosis

The diagnosis of multiple sclerosis (MS) is quite challenging due to its variable clinical manifestations and lack of a  definitive test. Magnetic resonance imaging (MRI) is one of the tools to confirm the diagnosis and also helps in differential diagnosis with other disorders and in exclusion of MS...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Alʹmanakh klinicheskoĭ medit͡s︡iny Jg. 49; H. 1; S. 89 - 97
Hauptverfasser: Krotenkova, I. A., Bryukhov, V. V., Konovalov, R. N., Zakharova, M. N., Krotenkova, M. V.
Format: Journal Article
Sprache:Russisch
Veröffentlicht: MONIKI 01.03.2021
Schlagworte:
ISSN:2072-0505, 2587-9294
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Abstract The diagnosis of multiple sclerosis (MS) is quite challenging due to its variable clinical manifestations and lack of a  definitive test. Magnetic resonance imaging (MRI) is one of the tools to confirm the diagnosis and also helps in differential diagnosis with other disorders and in exclusion of MS-mimicking diseases. In this article, based on the analysis of clinical cases, we discuss the differential diagnosis of MS with the following non-tumorous multifocal brain lesions: vascular abnormalities caused by hypoxia and ischemia, cerebral autosomal dominant angiopathy with subcortical infarctions and leukoencephalopathy, Susac syndrome, primary angiitis of the central nervous system, and neurosarcoidosis. We present both MRI criteria for MS and disorders that have similar MRI signs, and additional clinical and laboratory data that is essential for correct diagnosis.
AbstractList The diagnosis of multiple sclerosis (MS) is quite challenging due to its variable clinical manifestations and lack of a  definitive test. Magnetic resonance imaging (MRI) is one of the tools to confirm the diagnosis and also helps in differential diagnosis with other disorders and in exclusion of MS-mimicking diseases. In this article, based on the analysis of clinical cases, we discuss the differential diagnosis of MS with the following non-tumorous multifocal brain lesions: vascular abnormalities caused by hypoxia and ischemia, cerebral autosomal dominant angiopathy with subcortical infarctions and leukoencephalopathy, Susac syndrome, primary angiitis of the central nervous system, and neurosarcoidosis. We present both MRI criteria for MS and disorders that have similar MRI signs, and additional clinical and laboratory data that is essential for correct diagnosis.
Author Bryukhov, V. V.
Krotenkova, M. V.
Konovalov, R. N.
Zakharova, M. N.
Krotenkova, I. A.
Author_xml – sequence: 1
  givenname: I. A.
  orcidid: 0000-0001-5823-9434
  surname: Krotenkova
  fullname: Krotenkova, I. A.
– sequence: 2
  givenname: V. V.
  orcidid: 0000-0002-1645-6526
  surname: Bryukhov
  fullname: Bryukhov, V. V.
– sequence: 3
  givenname: R. N.
  orcidid: 0000-0001-5539-245X
  surname: Konovalov
  fullname: Konovalov, R. N.
– sequence: 4
  givenname: M. N.
  surname: Zakharova
  fullname: Zakharova, M. N.
– sequence: 5
  givenname: M. V.
  orcidid: 0000-0003-3820-4554
  surname: Krotenkova
  fullname: Krotenkova, M. V.
BookMark eNo9kdtOAyEQhompifXwCoYXWB1mOSyXxnhoUuONXhPKQkW3S4X2wreXrYcrJsw_H_zzn5LZmEZPyCWDK9apTl4jKGxAgGgQkDVcNwD8iMxRdKrRqPms1n-aE3JRyjsA1FmFDObk88muR7-LjmZf0mhH52nc2HUc1zSOdPfmaR-rJJVYaAq0Pt_s9puU077QzX7YxZCcHegq2yoffIlprI24ie5jYhwk28HT4gafJ8o5OQ52KP7i9zwjr_d3L7ePzfL5YXF7s2wctozXr0tlHUPrUYherCQ41a0kQ973reacd9pBi6HF1jmFVmgZpOo7CJbpILr2jCx-uH2y72abq6v8ZZKN5nCR8trYXI0P3mgIddKiRuDcorTCKSWZd45x6XRfWfKH5aqFkn345zEwhxzMtGMz7dhMORiuTc2h_QaJHH4Q
Cites_doi 10.1161/01.str.32.6.1318
10.25692/ACEN.2018.1.9
10.1097/BOR.0000000000000229
10.1136/jnnp-2017-315691
10.1212/WNL.0000000000002992
10.1016/S1474-4422(13)70124-8
10.17116/jnevro20171174175-80
10.1097/00005792-198801000-00002
10.1016/S1474-4422(17)30470-2
10.3174/ajnr.A6103
10.1177/1352458508096878
10.1097/01.dad.0000136691.96212.ec
10.1016/j.crad.2015.09.007
10.1016/j.msard.2018.04.012
10.22468/cvia.2016.00045
10.3174/ajnr.A5492
10.5935/1678-9741.20150022
10.1002/art.37715
10.1212/wnl.59.6.961
10.25697/MM.2019.01.08
10.1016/j.ncl.2014.12.004
10.1148/radiol.2531081103
10.1309/AJCPERI7LC4VNFYK
10.1002/9781118777329.ch24
10.25692/ACEN.2019.1.5
10.1016/j.crad.2016.05.010
10.1055/s2007-1014065
10.1385/ENDO:17:3:241
10.1007/s002340100583
10.17305/bjbms.2015.247
10.7197/1305-0028.1215
10.1161/HYPERTENSIONAHA.118.12090
10.1177/1352458516644677
10.1016/S1474-4422(15)00393-2
10.17116/jnevro201611610227-34
10.1186/s12916-017-0778-8
10.1007/s00234-019-02335-5
10.3174/ajnr.A1579
ContentType Journal Article
DBID AAYXX
CITATION
DOA
DOI 10.18786/2072-0505-2021-49-004
DatabaseName CrossRef
DOAJ (Directory of Open Access Journals)
DatabaseTitle CrossRef
DatabaseTitleList CrossRef

Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
DeliveryMethod fulltext_linktorsrc
EISSN 2587-9294
EndPage 97
ExternalDocumentID oai_doaj_org_article_90f7d8a292044a26a5c7761ecc146c9d
10_18786_2072_0505_2021_49_004
GroupedDBID AAYXX
ALMA_UNASSIGNED_HOLDINGS
CITATION
GROUPED_DOAJ
ID FETCH-LOGICAL-c2314-9267ac12ae255d5b60c78b6124dd3944489c032f323cc72a596f67d80fa19f583
IEDL.DBID DOA
ISSN 2072-0505
IngestDate Fri Oct 03 12:37:25 EDT 2025
Sat Nov 29 04:04:07 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Language Russian
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c2314-9267ac12ae255d5b60c78b6124dd3944489c032f323cc72a596f67d80fa19f583
ORCID 0000-0001-5539-245X
0000-0003-3820-4554
0000-0001-5823-9434
0000-0002-1645-6526
OpenAccessLink https://doaj.org/article/90f7d8a292044a26a5c7761ecc146c9d
PageCount 9
ParticipantIDs doaj_primary_oai_doaj_org_article_90f7d8a292044a26a5c7761ecc146c9d
crossref_primary_10_18786_2072_0505_2021_49_004
PublicationCentury 2000
PublicationDate 2021-03-01
PublicationDateYYYYMMDD 2021-03-01
PublicationDate_xml – month: 03
  year: 2021
  text: 2021-03-01
  day: 01
PublicationDecade 2020
PublicationTitle Alʹmanakh klinicheskoĭ medit͡s︡iny
PublicationYear 2021
Publisher MONIKI
Publisher_xml – name: MONIKI
References ref13
ref35
ref12
ref34
ref15
ref37
ref14
ref36
ref31
ref30
ref11
ref33
ref10
ref32
ref2
ref1
ref17
ref39
ref16
ref38
ref19
ref18
ref24
ref23
ref26
ref25
ref20
ref22
ref21
ref28
ref27
ref29
ref8
ref7
ref9
ref4
ref3
ref6
ref5
ref40
References_xml – ident: ref6
  doi: 10.1161/01.str.32.6.1318
– ident: ref11
  doi: 10.25692/ACEN.2018.1.9
– ident: ref29
  doi: 10.1097/BOR.0000000000000229
– ident: ref31
  doi: 10.1136/jnnp-2017-315691
– ident: ref36
  doi: 10.1212/WNL.0000000000002992
– ident: ref5
– ident: ref9
  doi: 10.1016/S1474-4422(13)70124-8
– ident: ref16
  doi: 10.17116/jnevro20171174175-80
– ident: ref27
  doi: 10.1097/00005792-198801000-00002
– ident: ref1
  doi: 10.1016/S1474-4422(17)30470-2
– ident: ref23
  doi: 10.3174/ajnr.A6103
– ident: ref3
  doi: 10.1177/1352458508096878
– ident: ref19
  doi: 10.1097/01.dad.0000136691.96212.ec
– ident: ref34
  doi: 10.1016/j.crad.2015.09.007
– ident: ref37
  doi: 10.1016/j.msard.2018.04.012
– ident: ref14
  doi: 10.22468/cvia.2016.00045
– ident: ref35
  doi: 10.3174/ajnr.A5492
– ident: ref13
  doi: 10.5935/1678-9741.20150022
– ident: ref26
  doi: 10.1002/art.37715
– ident: ref18
  doi: 10.1212/wnl.59.6.961
– ident: ref28
  doi: 10.25697/MM.2019.01.08
– ident: ref32
  doi: 10.1016/j.ncl.2014.12.004
– ident: ref30
– ident: ref38
  doi: 10.1148/radiol.2531081103
– ident: ref20
  doi: 10.1309/AJCPERI7LC4VNFYK
– ident: ref21
  doi: 10.1002/9781118777329.ch24
– ident: ref10
  doi: 10.25692/ACEN.2019.1.5
– ident: ref2
  doi: 10.1016/j.crad.2016.05.010
– ident: ref12
  doi: 10.1055/s2007-1014065
– ident: ref33
  doi: 10.1385/ENDO:17:3:241
– ident: ref39
  doi: 10.1007/s002340100583
– ident: ref17
  doi: 10.17305/bjbms.2015.247
– ident: ref22
  doi: 10.7197/1305-0028.1215
– ident: ref7
  doi: 10.1161/HYPERTENSIONAHA.118.12090
– ident: ref24
  doi: 10.1177/1352458516644677
– ident: ref8
  doi: 10.1016/S1474-4422(15)00393-2
– ident: ref4
  doi: 10.17116/jnevro201611610227-34
– ident: ref15
  doi: 10.1186/s12916-017-0778-8
– ident: ref25
  doi: 10.1007/s00234-019-02335-5
– ident: ref40
  doi: 10.3174/ajnr.A1579
SSID ssj0001877210
Score 2.1361022
Snippet The diagnosis of multiple sclerosis (MS) is quite challenging due to its variable clinical manifestations and lack of a  definitive test. Magnetic resonance...
SourceID doaj
crossref
SourceType Open Website
Index Database
StartPage 89
SubjectTerms differential diagnosis
magnetic resonance imaging
multiple sclerosis
non-tumorous multifocal brain lesions
Title Magnetic resonance imaging in the diagnosis of non-tumorous multifocal brain lesions mimicking multiple sclerosis
URI https://doaj.org/article/90f7d8a292044a26a5c7761ecc146c9d
Volume 49
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 2587-9294
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0001877210
  issn: 2072-0505
  databaseCode: DOA
  dateStart: 20130101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV09T8MwELUQYmBBIEB8ywOrVeM4_hgBgVioGEDqZjmXGEWiFNKW38-dk1bdWFidyLbeOfE96_weY9c-GV1KWYnSahDa-SR8BKQqsYikWKQL0Nlswo7HbjLxLxtWX1QT1ssD98CNvEy2dpFMlbSOysQSLFJvHBm_cfA1_X0x69kgU_l0xWHWmKUIlLRKkF3bcD3YWWdG60ZcJAon5oUcnNpWO9OGgH_eaR732d6QIvLbfmoHbKtbHrLv5_j-SRcOOfLjGalkNLydZosh3n5yTON43VfNtXM-SxxZvVgsp7MOmT3PVYOJdi1ekSUE_2jokAwftNMW6LCcrwoL-RzH7KiXI_b2-PB6_yQGuwQBmKRp4ZWxCLOKDdKEuqyMBOsqzGB0XdP1VwwEyEKlQhUAVsXSm2QQW5nijU-lK47ZNk6uOWFcQkqqSbFWIDUoGatUJme9AWlclapTNlpBFb56VYxAbILADQRuIHADgRu0DwjuKbsjRNdvk6p1bsBYhyHW4a9Yn_1HJ-dsNwc915FdsO1Ft2wu2Q78LNp5d5WX0S8EpslW
linkProvider Directory of Open Access Journals
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Magnetic+resonance+imaging+in+the+diagnosis+of+non-tumorous+multifocal+brain+lesions+mimicking+multiple+sclerosis&rft.jtitle=Al%CA%B9manakh+klinichesko%C4%AD+medit%CD%A1s%EF%B8%A1iny&rft.au=Krotenkova%2C+I.+A.&rft.au=Bryukhov%2C+V.+V.&rft.au=Konovalov%2C+R.+N.&rft.au=Zakharova%2C+M.+N.&rft.date=2021-03-01&rft.issn=2072-0505&rft.eissn=2587-9294&rft.volume=49&rft.issue=1&rft.spage=89&rft.epage=97&rft_id=info:doi/10.18786%2F2072-0505-2021-49-004&rft.externalDBID=n%2Fa&rft.externalDocID=10_18786_2072_0505_2021_49_004
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2072-0505&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2072-0505&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2072-0505&client=summon