The effect of acetylcysteine on the prothrombin time and international normalized ratio: a narrative review

Patients poisoned with paracetamol are treated with acetylcysteine. In patients without hepatocellular injury, an increased prothrombin time or international normalized ratio has been observed during acetylcysteine administration. The international normalized ratio is preferred as it is a standardiz...

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Bibliographic Details

Published in:	Clinical toxicology (Philadelphia, Pa.) Vol. 63; no. 3; pp. 166 - 175
Main Authors:	Nazar, Messia, Kootstra-Ros, Jenny E., Mian, Paola, Touw, Daniel J., Sturkenboom, Marieke G. G.
Format:	Journal Article
Language:	English
Published:	England 01.03.2025
Subjects:	Acetaminophen - poisoning Acetylcysteine - pharmacology Acetylcysteine - therapeutic use Analgesics, Non-Narcotic - poisoning Blood Coagulation - drug effects Chemical and Drug Induced Liver Injury - blood Humans International Normalized Ratio Prothrombin Time Acetylcysteine prothrombin time coagulation factor activity narrative review international normalized ratio
ISSN:	1556-3650, 1556-9519, 1556-9519
Online Access:	Get full text
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