Compliance With Recommendations of the Surveillance, Epidemiology, and End Results (SEER) Treatment Data Use Agreement: A Review of Published Studies

The Surveillance, Epidemiology, and End Results (SEER) Program collects data on the first course of cancer treatment, but no and unknown receipt of treatment cannot be distinguished for radiation therapy (RT) and chemotherapy. As part of the Data Use Agreement (DUA), users must acknowledge that they...

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Vydáno v:Medical care Ročník 63; číslo 12; s. 899
Hlavní autoři: Hong, Yoon Duk, Mariotto, Angela B, Lewis, Denise R, Noone, Anne-Michelle, Howlader, Nadia, Scoppa, Steve, Feuer, Eric J
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.12.2025
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ISSN:1537-1948, 1537-1948
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Abstract The Surveillance, Epidemiology, and End Results (SEER) Program collects data on the first course of cancer treatment, but no and unknown receipt of treatment cannot be distinguished for radiation therapy (RT) and chemotherapy. As part of the Data Use Agreement (DUA), users must acknowledge that they understand the data limitations and agree to include a description of the limitations in any analyses published using the data. The objective of this review was to evaluate users' compliance with the recommendations of the DUA. Publications from a PubMed search were matched with the names of SEER treatment data users, and keywords were applied to identify relevant studies. Five reviewers (with 2 per publication) independently assessed if the authors (a) conducted analyses supported by these data, (b) correctly labelled no/unknown treatment as "no/unknown", and (c) described the limitations of their use. Publications were classified as "followed recommendations", "partially followed recommendations", or "did not follow recommendations" of the DUA. Among a total of 120 studies included in the review, 106 (88.3%) studies did not follow recommendations, 11 (9.2%) partially followed recommendations, and 3 studies (2.5%) followed recommendations. Only 11.7% of publications correctly labelled the "no/unknown" category as "no/unknown", and described the limitations associated with the no/unknown issue. In this review, we found substantial misuse of the SEER treatment data and limited acknowledgement of the limitations of the SEER treatment data in publications. Such findings highlight the need to think of effective ways of encouraging appropriate use of the treatment data.
AbstractList The Surveillance, Epidemiology, and End Results (SEER) Program collects data on the first course of cancer treatment, but no and unknown receipt of treatment cannot be distinguished for radiation therapy (RT) and chemotherapy. As part of the Data Use Agreement (DUA), users must acknowledge that they understand the data limitations and agree to include a description of the limitations in any analyses published using the data. The objective of this review was to evaluate users' compliance with the recommendations of the DUA. Publications from a PubMed search were matched with the names of SEER treatment data users, and keywords were applied to identify relevant studies. Five reviewers (with 2 per publication) independently assessed if the authors (a) conducted analyses supported by these data, (b) correctly labelled no/unknown treatment as "no/unknown", and (c) described the limitations of their use. Publications were classified as "followed recommendations", "partially followed recommendations", or "did not follow recommendations" of the DUA. Among a total of 120 studies included in the review, 106 (88.3%) studies did not follow recommendations, 11 (9.2%) partially followed recommendations, and 3 studies (2.5%) followed recommendations. Only 11.7% of publications correctly labelled the "no/unknown" category as "no/unknown", and described the limitations associated with the no/unknown issue. In this review, we found substantial misuse of the SEER treatment data and limited acknowledgement of the limitations of the SEER treatment data in publications. Such findings highlight the need to think of effective ways of encouraging appropriate use of the treatment data.
The Surveillance, Epidemiology, and End Results (SEER) Program collects data on the first course of cancer treatment, but no and unknown receipt of treatment cannot be distinguished for radiation therapy (RT) and chemotherapy. As part of the Data Use Agreement (DUA), users must acknowledge that they understand the data limitations and agree to include a description of the limitations in any analyses published using the data. The objective of this review was to evaluate users' compliance with the recommendations of the DUA.INTRODUCTIONThe Surveillance, Epidemiology, and End Results (SEER) Program collects data on the first course of cancer treatment, but no and unknown receipt of treatment cannot be distinguished for radiation therapy (RT) and chemotherapy. As part of the Data Use Agreement (DUA), users must acknowledge that they understand the data limitations and agree to include a description of the limitations in any analyses published using the data. The objective of this review was to evaluate users' compliance with the recommendations of the DUA.Publications from a PubMed search were matched with the names of SEER treatment data users, and keywords were applied to identify relevant studies. Five reviewers (with 2 per publication) independently assessed if the authors (a) conducted analyses supported by these data, (b) correctly labelled no/unknown treatment as "no/unknown", and (c) described the limitations of their use. Publications were classified as "followed recommendations", "partially followed recommendations", or "did not follow recommendations" of the DUA.METHODSPublications from a PubMed search were matched with the names of SEER treatment data users, and keywords were applied to identify relevant studies. Five reviewers (with 2 per publication) independently assessed if the authors (a) conducted analyses supported by these data, (b) correctly labelled no/unknown treatment as "no/unknown", and (c) described the limitations of their use. Publications were classified as "followed recommendations", "partially followed recommendations", or "did not follow recommendations" of the DUA.Among a total of 120 studies included in the review, 106 (88.3%) studies did not follow recommendations, 11 (9.2%) partially followed recommendations, and 3 studies (2.5%) followed recommendations. Only 11.7% of publications correctly labelled the "no/unknown" category as "no/unknown", and described the limitations associated with the no/unknown issue.RESULTSAmong a total of 120 studies included in the review, 106 (88.3%) studies did not follow recommendations, 11 (9.2%) partially followed recommendations, and 3 studies (2.5%) followed recommendations. Only 11.7% of publications correctly labelled the "no/unknown" category as "no/unknown", and described the limitations associated with the no/unknown issue.In this review, we found substantial misuse of the SEER treatment data and limited acknowledgement of the limitations of the SEER treatment data in publications. Such findings highlight the need to think of effective ways of encouraging appropriate use of the treatment data.CONCLUSIONSIn this review, we found substantial misuse of the SEER treatment data and limited acknowledgement of the limitations of the SEER treatment data in publications. Such findings highlight the need to think of effective ways of encouraging appropriate use of the treatment data.
Author Howlader, Nadia
Lewis, Denise R
Hong, Yoon Duk
Noone, Anne-Michelle
Feuer, Eric J
Scoppa, Steve
Mariotto, Angela B
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  givenname: Eric J
  surname: Feuer
  fullname: Feuer, Eric J
  organization: Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD
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cancer treatment
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SubjectTerms Guideline Adherence - statistics & numerical data
Humans
Neoplasms - therapy
SEER Program - standards
SEER Program - statistics & numerical data
United States
Title Compliance With Recommendations of the Surveillance, Epidemiology, and End Results (SEER) Treatment Data Use Agreement: A Review of Published Studies
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