Preliminary Investigation of a Novel 18F Radiopharmaceutical for Imaging CB2 Receptors in a SOD Mouse Model

We successfully radiolabelled a novel prospective cannabinoid type 2 receptor ligand with F-18 and tested its biodistribution in animal models by positron emission tomography (PET)/computed tomography (CT) imaging. The radiolabelling process was conducted on an alkyl mesylate fragment of the main na...

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Bibliographic Details
Published in:	Australian journal of chemistry Vol. 74; no. 6; pp. 443 - 452
Main Authors:	Pascali, Giancarlo, Panetta, Daniele, De Simone, Mariarosaria, Burchielli, Silvia, Lucchesi, Valentina, Sanguinetti, Elena, Zanoni, Simone, Iozzo, Patricia, Saccomanni, Giuseppe, Manera, Clementina, Salvadori, Piero A.
Format:	Journal Article
Language:	English
Published:	CLAYTON SOUTH Csiro Publishing 01.01.2021 CSIRO
Subjects:	Amyotrophic lateral sclerosis Brain research Chemistry Chemistry, Multidisciplinary Computed tomography Fluorine isotopes Investigations Medical imaging Optimization Physical Sciences Positron emission Radiochemistry Radiolabelling Receptors Science & Technology Tomography GRAPHICAL ANALYSIS LIGANDS FLEXIBILITY HEALTHY DERIVATIVES BINDING PET RATIONAL DESIGN
ISSN:	0004-9425, 1529-5036, 1445-0038
Online Access:	Get full text
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