2.1 THE RELATIVE IMPORTANCE OF CENTRAL AND BRACHIAL BLOOD PRESSURE IN PREDICTING CARDIOVASCULAR EVENTS: AN INDIVIDUAL PARTICIPANT META-ANALYSIS OF PROSPECTIVE OBSERVATIONAL DATA FROM 22,433 SUBJECTS
Systolic blood pressure (SBP) differs between the brachial artery and aorta. Prospective data suggest that central pressure predicts future cardiovascular events, but it is unclear if it is superior to brachial pressure. Methods and Results: A systematic review and individual participant data meta-a...
Uloženo v:
| Vydáno v: | Artery research Ročník 16; číslo C; s. 49 |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
BMC
01.11.2016
|
| ISSN: | 1876-4401, 1876-4401 |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Systolic blood pressure (SBP) differs between the brachial artery and aorta. Prospective data suggest that central pressure predicts future cardiovascular events, but it is unclear if it is superior to brachial pressure. Methods and Results: A systematic review and individual participant data meta-analysis from 15 studies was undertaken. Study-specific associations of central and brachial pressure with cardiovascular outcomes, with and without mutual adjustment, were determined using Cox proportional hazard models, and random effect models to estimate pooled estimates. Of 22,433 participants, 908 had a myocardial infarction (MI) and 641 a stroke. The pooled age, sex, height and heart rate adjusted hazard ratio (HR) [95% CI] per SD increase in brachial SBP was 1.17 [1.03, 1.32] for MI and 1.28 [1.13, 1.46] for stroke and 1.16 [1.02, 1.33] and 1.33 [1.15, 1.53] for central SBP, respectively. Mutual adjustment attenuated the HRs for MI: brachial SBP (1.16 [0.90, 1.48]), central SBP (1.09 [0.87, 1.38]) and stroke: brachial SBP (1.18 [0.97, 1.42]), central SBP (1.19 [0.99, 1.44]). However, associations between central SBP and stroke, after adjustment for brachial SBP, were higher in those aged <61 years than in older individuals (1.83 versus 1.08 p-interaction <0.001). Conclusion: Brachial and central SBP have similar associations with future CV events. Larger studies are required to test whether central SBP may be a more powerful predictor of stroke risk in younger individuals. |
|---|---|
| AbstractList | Systolic blood pressure (SBP) differs between the brachial artery and aorta. Prospective data suggest that central pressure predicts future cardiovascular events, but it is unclear if it is superior to brachial pressure. Methods and Results: A systematic review and individual participant data meta-analysis from 15 studies was undertaken. Study-specific associations of central and brachial pressure with cardiovascular outcomes, with and without mutual adjustment, were determined using Cox proportional hazard models, and random effect models to estimate pooled estimates. Of 22,433 participants, 908 had a myocardial infarction (MI) and 641 a stroke. The pooled age, sex, height and heart rate adjusted hazard ratio (HR) [95% CI] per SD increase in brachial SBP was 1.17 [1.03, 1.32] for MI and 1.28 [1.13, 1.46] for stroke and 1.16 [1.02, 1.33] and 1.33 [1.15, 1.53] for central SBP, respectively. Mutual adjustment attenuated the HRs for MI: brachial SBP (1.16 [0.90, 1.48]), central SBP (1.09 [0.87, 1.38]) and stroke: brachial SBP (1.18 [0.97, 1.42]), central SBP (1.19 [0.99, 1.44]). However, associations between central SBP and stroke, after adjustment for brachial SBP, were higher in those aged <61 years than in older individuals (1.83 versus 1.08 p-interaction <0.001). Conclusion: Brachial and central SBP have similar associations with future CV events. Larger studies are required to test whether central SBP may be a more powerful predictor of stroke risk in younger individuals. |
| Author | Pini, Riccardo Chen, Chen-Huan Dart, Anthony Hwang, Shih-Jen Jankowski, Piotr Jacobs, David Cameron, James Lacy, Peter Mitchell, Gary Devereux, Richard May, Margaret Brumback, Lyndia McEniery, Carmel Spears, Melissa Chirinos, Julio Dhaun, Neeraj Duprez, Daniel Janner, Julie Ben-Shlomo, Yoav Czarnecka, Danuta |
| Author_xml | – sequence: 1 givenname: Carmel surname: McEniery fullname: McEniery, Carmel – sequence: 2 givenname: Yoav surname: Ben-Shlomo fullname: Ben-Shlomo, Yoav – sequence: 3 givenname: Margaret surname: May fullname: May, Margaret – sequence: 4 givenname: Melissa surname: Spears fullname: Spears, Melissa – sequence: 5 givenname: Lyndia surname: Brumback fullname: Brumback, Lyndia – sequence: 6 givenname: James surname: Cameron fullname: Cameron, James – sequence: 7 givenname: Chen-Huan surname: Chen fullname: Chen, Chen-Huan – sequence: 8 givenname: Julio surname: Chirinos fullname: Chirinos, Julio – sequence: 9 givenname: Danuta surname: Czarnecka fullname: Czarnecka, Danuta – sequence: 10 givenname: Anthony surname: Dart fullname: Dart, Anthony – sequence: 11 givenname: Richard surname: Devereux fullname: Devereux, Richard – sequence: 12 givenname: Neeraj surname: Dhaun fullname: Dhaun, Neeraj – sequence: 13 givenname: Daniel surname: Duprez fullname: Duprez, Daniel – sequence: 14 givenname: Shih-Jen surname: Hwang fullname: Hwang, Shih-Jen – sequence: 15 givenname: David surname: Jacobs fullname: Jacobs, David – sequence: 16 givenname: Piotr surname: Jankowski fullname: Jankowski, Piotr – sequence: 17 givenname: Julie surname: Janner fullname: Janner, Julie – sequence: 18 givenname: Peter surname: Lacy fullname: Lacy, Peter – sequence: 19 givenname: Gary surname: Mitchell fullname: Mitchell, Gary – sequence: 20 givenname: Riccardo surname: Pini fullname: Pini, Riccardo |
| BookMark | eNp9Uc2OmzAYRNVW6u62b9CDH6CktjEG9uaAs3FFAJkfqSfLAbsiSkMFuewL9rlqNq1U9VBf_H2jmflGmgfv7jJdjOd9RHCDIKKfTxs9X2ezbLDbHLSBMHzj3aM4oj4hEN39Nb_zHpbl5AgRgvTe-4k3CDR7DiTPWSM6DsShKmXDipSDcgdSXjSS5YAVGdhKlu6FW7Z5WWagkryuW-kUxTpnIm1E8QxSJjNRdqxO25xJwDvnUD85A8fLRCey1jlUTDYiFRUrGnDgDfNZwfKvtajXm5Us64qnr2nKbc1l55KVjgAy1jCwk-UBYPyJBAGo2-0Xx6zfe2-tPi_mw-__0Wt3vEn3fl4-i5Tlfo9hHPo2iTUNrdFkwO7RY69DY1GQhAM11NKA6sFGODnCGIck7mFvcKB7i4kxOkxQ8OiJm-8w6ZP6MY_f9fyiJj2qV2CavylXxdifjSJRaClFx6g3liRI6wHHFmpCjpjYIKTO6-nm1c_TsszGqn686us4Xa6zHs8KQbW2q07q1q5a211RV54Tk3_Ef8L8V_YLvWme8Q |
| CitedBy_id | crossref_primary_10_1097_HJH_0000000000002828 |
| ContentType | Journal Article |
| DBID | AAYXX CITATION DOA |
| DOI | 10.1016/j.artres.2016.10.005 |
| DatabaseName | CrossRef Directory of Open Access Journals |
| DatabaseTitle | CrossRef |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology |
| EISSN | 1876-4401 |
| ExternalDocumentID | oai_doaj_org_article_475f661b7cef491aad28f0a44b24f356 10_1016_j_artres_2016_10_005 |
| GroupedDBID | --- --K --M .1- .FO .~1 0R~ 1B1 1P~ 1~. 1~5 23N 4.4 457 4G. 53G 5GY 5VS 7-5 71M 7X7 8FI 8FJ 8P~ 9DU AAEDT AAIKJ AAJSJ AAKKN AALRI AAOAW AAQFI AASML AAXUO AAYXX ABBQC ABEEZ ABMZM ABUWG ABWVN ABXDB ACACY ACGFS ACRPL ACULB ADBBV ADEZE ADMUD ADNMO ADUKV AEKER AEVXI AFFHD AFGXO AFKRA AFRHN AGHFR AGUBO AGYEJ AIGII AITUG AJRQY AJUYK ALMA_UNASSIGNED_HOLDINGS ANZVX BENPR BLXMC BMC C24 C6C CCPQU CITATION CS3 EBLON EBS EFLBG EJD EMOBN EO9 EP2 EP3 F5P FDB FEDTE FIRID FNPLU FYUFA GBLVA GROUPED_DOAJ HMCUK HVGLF HZ~ IHE J1W M41 MO0 N9A O-L O9- OAUVE OA~ OK1 OL0 OZT P-8 P-9 P2P PC. PHGZM PHGZT PIMPY Q38 ROL RPZ SDF SDG SEL SES SOJ UKHRP Z5R ~G- ~HD |
| ID | FETCH-LOGICAL-c2085-f98a65fea4d22226bca5ef1395d6e6f636adf729b082548c0ce23acf24eea5913 |
| IEDL.DBID | DOA |
| ISSN | 1876-4401 |
| IngestDate | Tue Oct 14 19:08:11 EDT 2025 Sat Nov 29 02:07:09 EST 2025 Tue Nov 18 21:57:21 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | C |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c2085-f98a65fea4d22226bca5ef1395d6e6f636adf729b082548c0ce23acf24eea5913 |
| OpenAccessLink | https://doaj.org/article/475f661b7cef491aad28f0a44b24f356 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_475f661b7cef491aad28f0a44b24f356 crossref_citationtrail_10_1016_j_artres_2016_10_005 crossref_primary_10_1016_j_artres_2016_10_005 |
| PublicationCentury | 2000 |
| PublicationDate | 2016-11-01 |
| PublicationDateYYYYMMDD | 2016-11-01 |
| PublicationDate_xml | – month: 11 year: 2016 text: 2016-11-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationTitle | Artery research |
| PublicationYear | 2016 |
| Publisher | BMC |
| Publisher_xml | – name: BMC |
| SSID | ssj0057106 |
| Score | 2.0052624 |
| Snippet | Systolic blood pressure (SBP) differs between the brachial artery and aorta. Prospective data suggest that central pressure predicts future cardiovascular... |
| SourceID | doaj crossref |
| SourceType | Open Website Enrichment Source Index Database |
| StartPage | 49 |
| Title | 2.1 THE RELATIVE IMPORTANCE OF CENTRAL AND BRACHIAL BLOOD PRESSURE IN PREDICTING CARDIOVASCULAR EVENTS: AN INDIVIDUAL PARTICIPANT META-ANALYSIS OF PROSPECTIVE OBSERVATIONAL DATA FROM 22,433 SUBJECTS |
| URI | https://doaj.org/article/475f661b7cef491aad28f0a44b24f356 |
| Volume | 16 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1876-4401 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0057106 issn: 1876-4401 databaseCode: 7X7 dateStart: 20060601 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1876-4401 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0057106 issn: 1876-4401 databaseCode: BENPR dateStart: 20060601 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Publicly Available Content Database customDbUrl: eissn: 1876-4401 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0057106 issn: 1876-4401 databaseCode: PIMPY dateStart: 20060601 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lj9MwELZgxYELAhbE8lj5gDiRpY0fSbi5SUottUmUpFU5RY5jSyAoaFmQ-IP8LsZOulpOe-HmWPZk5BllZqLx9yH0enAxquc6sGpmAmpmKoi1jmBEkoHZGHJU6skmoqKI9_ukukH15XrCRnjg8eDe0YhZiCF9pI2lyVypIYztTFHah9QS5sG2Ies5FlPjN5hB3OTHi3K-mwvEQfnqWrn4he_mYv8Eoht4_T6wLB-iB1NGiMWoySN0xxweo1NxgGr462_8BvseTf_z-xT9CS_muF3l2DFdtHKXY7mpyrp1DDO4XOI0LxwHMhZFhhe1SFcSHhbrssywP-ptDTsKN85k2sriA05FnclyJ5p0uxY1zncgoXkPAmBdJncy24KECrJemcpKFC3e5K0IRCHWHxvZuHdWddlUeeq1KRdNXu8mgF2ciVbgZV1ucBi-pYTgiV2leYK2y7xNV8HExBBox-EZ2CRWnFmj6AD5RMh7rZixkDyygRtuOeFqsJCm977gjPVMm5AobUNqjGLJnDxFJ4dvB_MMYdWThM81UzEh1IHPsHmcRIzHw0D7hOozRI5m6fQEU-7YMr50x360z91ozM4Z082CMc9QcL3r-wjTccv6hbP49VoHsu0nwPW6yfW621zv-f8Q8gLdd3qN1xtfopOry5_mFbqnf119-nF5ju5G--jc-_ZfB3jumg |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=2.1+THE+RELATIVE+IMPORTANCE+OF+CENTRAL+AND+BRACHIAL+BLOOD+PRESSURE+IN+PREDICTING+CARDIOVASCULAR+EVENTS%3A+AN+INDIVIDUAL+PARTICIPANT+META-ANALYSIS+OF+PROSPECTIVE+OBSERVATIONAL+DATA+FROM+22%2C433+SUBJECTS&rft.jtitle=Artery+research&rft.au=Carmel+McEniery&rft.au=Yoav+Ben-Shlomo&rft.au=Margaret+May&rft.au=Melissa+Spears&rft.date=2016-11-01&rft.pub=BMC&rft.eissn=1876-4401&rft.volume=16&rft_id=info:doi/10.1016%2Fj.artres.2016.10.005&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_475f661b7cef491aad28f0a44b24f356 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1876-4401&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1876-4401&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1876-4401&client=summon |