EPS3.02A preferential orientation adipocyte differentiation of CFTR-mutated mesenchymal stem cells: predisposing factor to cystic fibrosis-related bone diseases

Cystic Fibrosis-related Bone Disease (CFBD) affects 50% of CF adult patients. Osteoblasts obtained from CF induced pluripotent stem cells (iPSCs) evidenced a higher PPARG level (adipocyte transcription factor) than healthy control line. In several pathologies, a relationship exists between low bone...

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Bibliographic Details
Published in:Journal of cystic fibrosis Vol. 24; p. S46
Main Authors: Hamon, L., Dumortier, C., Thoraval, L., Sergheraert, J., Piot, O., Buache, E., Goffin, N., Chauveau, C., Gangloff, S., Alam, D. Al, Jourdain, M.-L., Velard, F.
Format: Journal Article
Language:English
Published: Elsevier B.V 01.06.2025
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ISSN:1569-1993
Online Access:Get full text
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