Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution. 1. Physiologic concepts

The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of two part series, are summarized the physiologic principles on which the analysis of...

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Bibliographic Details
Published in:Intensive care medicine Vol. 20; no. 4; p. 291
Main Authors: Marshall, B E, Marshall, C, Frasch, F, Hanson, C W
Format: Journal Article
Language:English
Published: United States 01.04.1994
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ISSN:0342-4642
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Summary:The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of two part series, are summarized the physiologic principles on which the analysis of ventilation/perfusion ratios and of pressure-flow relationships are based. A new combined analysis is introduced that permits the important contributions of hypoxic pulmonary vasoconstriction to overall gas exchange to be demonstrated in the circumstances of clinical complexity.
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ISSN:0342-4642
DOI:10.1007/BF01708968