Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution. 1. Physiologic concepts

The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of two part series, are summarized the physiologic principles on which the analysis of...

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Veröffentlicht in:	Intensive care medicine Jg. 20; H. 4; S. 291
Hauptverfasser:	Marshall, B E, Marshall, C, Frasch, F, Hanson, C W
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.04.1994
Schlagworte:	Humans Hypoxia - physiopathology Pulmonary Artery - physiology Pulmonary Circulation - physiology Pulmonary Gas Exchange - physiology Pulmonary Veins - physiology Vasoconstriction - physiology Ventilation-Perfusion Ratio - physiology
ISSN:	0342-4642
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Zusammenfassung:	The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of two part series, are summarized the physiologic principles on which the analysis of ventilation/perfusion ratios and of pressure-flow relationships are based. A new combined analysis is introduced that permits the important contributions of hypoxic pulmonary vasoconstriction to overall gas exchange to be demonstrated in the circumstances of clinical complexity.
Bibliographie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	0342-4642
DOI:	10.1007/BF01708968