Phosphorylation of histone H3T6 by PKCβI controls demethylation at histone H3K4

Histone demethylation mechanisms The N-terminal tails of histones are subject to a variety of post-translational modifications; addition or removal of these marks by specific enzymes facilitates gene activation or silencing. Here, a mechanism is defined that modulates the activity of the dual specif...

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Bibliographic Details
Published in:Nature (London) Vol. 464; no. 7289; pp. 792 - 796
Main Authors: Metzger, Eric, Imhof, Axel, Patel, Dharmeshkumar, Kahl, Philip, Hoffmeyer, Katrin, Friedrichs, Nicolaus, Müller, Judith M., Greschik, Holger, Kirfel, Jutta, Ji, Sujuan, Kunowska, Natalia, Beisenherz-Huss, Christian, Günther, Thomas, Buettner, Reinhard, Schüle, Roland
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 01.04.2010
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ISSN:0028-0836, 1476-4687
Online Access:Get full text
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