Elucidation of roles for vitamin B 12 in regulation of folate, ubiquinone, and methionine metabolism

Only a small fraction of vitamin B -requiring organisms are able to synthesize B de novo, making it a common commodity in microbial communities. Initially recognized as an enzyme cofactor of a few enzymes, recent studies have revealed additional B -binding enzymes and regulatory roles for B Here we...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 114; no. 7; p. E1205
Main Authors:	Romine, Margaret F, Rodionov, Dmitry A, Maezato, Yukari, Anderson, Lindsey N, Nandhikonda, Premchendar, Rodionova, Irina A, Carre, Alexandre, Li, Xiaoqing, Xu, Chengdong, Clauss, Therese R W, Kim, Young-Mo, Metz, Thomas O, Wright, Aaron T
Format:	Journal Article
Language:	English
Published:	United States 14.02.2017
Subjects:	Amino Acid Sequence Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Base Sequence Biochemical Phenomena - radiation effects Folic Acid - metabolism Gammaproteobacteria - genetics Gammaproteobacteria - metabolism Halomonas - genetics Halomonas - metabolism Methionine - metabolism Protein Binding - radiation effects Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Ubiquinone - metabolism Ultraviolet Rays Vitamin B 12 - chemistry Vitamin B 12 - metabolism metabolism cobalamin chemical biology microbial regulation
ISSN:	1091-6490
Online Access:	Get more information
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