Molecular genetic methods for quality control of inactivated vaccines using a Chikungunya virus model: vaccine strain identification and completeness of virus inactivation

INTRODUCTION. The completeness of virus inactivation and the identity of the vaccine strain are essential parameters for the safety and quality of inactivated virus vaccines, which should be controlled during vaccine development and production. Currently, the most promising quality control methods f...

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Vydané v:	Biopreparaty Ročník 24; číslo 3; s. 279 - 293
Hlavní autori:	Oksanich, A. S., Samartseva, T. G., Kaa, K. V., Otrashevskaia, E. V., Krasko, A. G., Laputina, A. G., Netesova, N. A., Ignatyev, G. M.
Médium:	Magazine Article
Jazyk:	English Russian
Vydavateľské údaje:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products 03.10.2024
Predmet:	chikungunya virus integrated cell culture quantitative pcr restriction fragment length polymorphism method reverse transcription polymerase chain reaction
ISSN:	2221-996X, 2619-1156
On-line prístup:	Získať plný text
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