γ-PNA PREORGANIZATION: SYNTHESIS OF MODEL DIMER AND ITS STRUCTURE STUDY BY 2D NMR SPECTROSCOPY

The synthesis of a dimer consisting of γ-thymine chiral monomer based on L-Ala and thymine aeg-PNA monomer (synthesized from deuterated glycine), in which the methylene protons of the pseudopeptide residue were exchanged with deuterium atoms, was described. The deuterated monomer was introduced into...

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Bibliographic Details

Published in:	Fine Chemical Technologies Vol. 12; no. 2; pp. 62 - 71
Main Authors:	Dezhenkov, A. V., Cheshkov, D. A., Prokhorov, I. A., Lutik, A. I., Kirillova, Yu. G.
Format:	Journal Article
Language:	English Russian
Published:	MIREA - Russian Technological University 28.04.2017
Subjects:	dqf-cosy-nmr spectroscopy dqf-cosy-ямр-спектроскопия peptide nucleic acid pna pna chiral monomers pna preorganization pseudopeptides
ISSN:	2410-6593, 2686-7575
Online Access:	Get full text
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