Ten Reasons Why Prospective Randomized Studies in Surgery Are Flawed and Fundamentally Different From Drug Trials

Prospective randomized controlled trials are widely regarded as the gold standard for evaluating therapeutic interventions. Although this model is appropriate for drug development, its application in surgical research has proven challenging and, in many cases, misleading. Surgery involves complex in...

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Bibliographic Details
Published in:	The Journal of hand surgery (American ed.)
Main Authors:	Shin, Alexander Y, de Pinal, Francisco
Format:	Journal Article
Language:	English
Published:	United States 31.10.2025
Subjects:	Drug trials prospective randomized studies in surgery
ISSN:	1531-6564, 1531-6564
Online Access:	Get more information
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