Ten Reasons Why Prospective Randomized Studies in Surgery Are Flawed and Fundamentally Different From Drug Trials

Prospective randomized controlled trials are widely regarded as the gold standard for evaluating therapeutic interventions. Although this model is appropriate for drug development, its application in surgical research has proven challenging and, in many cases, misleading. Surgery involves complex in...

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Veröffentlicht in:The Journal of hand surgery (American ed.)
Hauptverfasser: Shin, Alexander Y, de Pinal, Francisco
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 31.10.2025
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ISSN:1531-6564, 1531-6564
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