Typical and atypical optic neuritis

Optic neuritis (ON) is one of the most common neuro-ophthalmic causes of vision loss worldwide. Demyelinating ON can be idiopathic or be one of the symptoms of autoimmune demyelinating diseases of the central nervous system (CNS) such as multiple sclerosis (MS), neuromyelitis optica spectrum disorde...

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Bibliographic Details
Published in:Vestnik oftal'mologii Vol. 139; no. 6; p. 175
Main Authors: Sheremet, N L, Eliseeva, D D, Kalashnikova, A K, Zakharova, M N
Format: Journal Article
Language:English
Russian
Published: Russia (Federation) 2023
Subjects:
Autoantibodies
Humans
Multiple Sclerosis - complications
Multiple Sclerosis - diagnosis
Myelin-Oligodendrocyte Glycoprotein
Neuromyelitis Optica - complications
Neuromyelitis Optica - diagnosis
Optic Neuritis - diagnosis
Optic Neuritis - etiology
Optic Neuritis - therapy
MOG-associated disease
neuromyelitis optica spectrum disorder
optic neuritis
ISSN:0042-465X
Online Access:Get more information
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Description
Summary:Optic neuritis (ON) is one of the most common neuro-ophthalmic causes of vision loss worldwide. Demyelinating ON can be idiopathic or be one of the symptoms of autoimmune demyelinating diseases of the central nervous system (CNS) such as multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Demographic, clinical and radiological signs of ON in these CNS diseases have differences. In this regard, typical and atypical ON are currently distinguished. Recognizing the clinical features that differentiate typical MS-associated ON from atypical ON in NMOSD and MOGAD is important for choosing the correct disease management and treatment strategy. This review summarizes the data from clinical, laboratory, instrumental methods of management used for the differential diagnosis of optic neuritis.
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ISSN:0042-465X
DOI:10.17116/oftalma2023139061175