Contribution of wide field angiography to diabetic macular edema

Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a retrospective study, consecutive wide‐field angiographs using the Heidelberg Retina Angiograph 2 with a contact lens system Staurenghi and SD‐OCT were...

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Published in:Acta ophthalmologica (Oxford, England) Vol. 94; no. S256
Main Authors: Maamouri, R., Bouraoui, R., Kort, F., Falfoul, Y., El Matri, K., El Matri, L.
Format: Journal Article
Language:English
Published: Malden Wiley Subscription Services, Inc 01.10.2016
Subjects:
Acuity
Angiography
Company reports
Diabetes
Diabetes mellitus
Diabetic retinopathy
Edema
Eye lens
Fluorescein
Medical imaging
Ophthalmology
Perfusion
Retina
Retinopathy
Vascular endothelial growth factor
ISSN:1755-375X, 1755-3768
Online Access:Get full text
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Summary:Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a retrospective study, consecutive wide‐field angiographs using the Heidelberg Retina Angiograph 2 with a contact lens system Staurenghi and SD‐OCT were performed in diabetic patients with non proliferative diabetic retinopathy. Results A total of 71 eyes in 39 diabetic, average age was 58 years (SD 12). Most of the patients had type 2 diabetes mellitus (92%) and average duration since diabetes diagnosis was 10 years. Mean HA1c was 7.4%. Distribution of NPDR severity was: mild NPDR in 6% of eyes, moderate NPDR in 21% and severe NPDR in 73%. Macular edema was found in 53%. A thicker retina was observed in eyes with peripheral non perfusion (353 vs. 254 μm p = 0.006). Retinal non perfusion was associated with macular edema (97 vs. 76%, p = 0.01) and poor visual acuity (p < 0.001). Conclusions Diabetic macular edema seems to be strongly associated with peripheral retinal non perfusion. So treatment and management of diabetic macular edema may be reconsidered using either a targeted laser treatment in the area of retinal non perfusion or anti‐VEGF intravitreal injection.
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ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2016.0491