Contribution of wide field angiography to diabetic macular edema

Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a retrospective study, consecutive wide‐field angiographs using the Heidelberg Retina Angiograph 2 with a contact lens system Staurenghi and SD‐OCT were...

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Veröffentlicht in:Acta ophthalmologica (Oxford, England) Jg. 94; H. S256
Hauptverfasser: Maamouri, R., Bouraoui, R., Kort, F., Falfoul, Y., El Matri, K., El Matri, L.
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Sprache:Englisch
Veröffentlicht: Malden Wiley Subscription Services, Inc 01.10.2016
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ISSN:1755-375X, 1755-3768
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Abstract Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a retrospective study, consecutive wide‐field angiographs using the Heidelberg Retina Angiograph 2 with a contact lens system Staurenghi and SD‐OCT were performed in diabetic patients with non proliferative diabetic retinopathy. Results A total of 71 eyes in 39 diabetic, average age was 58 years (SD 12). Most of the patients had type 2 diabetes mellitus (92%) and average duration since diabetes diagnosis was 10 years. Mean HA1c was 7.4%. Distribution of NPDR severity was: mild NPDR in 6% of eyes, moderate NPDR in 21% and severe NPDR in 73%. Macular edema was found in 53%. A thicker retina was observed in eyes with peripheral non perfusion (353 vs. 254 μm p = 0.006). Retinal non perfusion was associated with macular edema (97 vs. 76%, p = 0.01) and poor visual acuity (p < 0.001). Conclusions Diabetic macular edema seems to be strongly associated with peripheral retinal non perfusion. So treatment and management of diabetic macular edema may be reconsidered using either a targeted laser treatment in the area of retinal non perfusion or anti‐VEGF intravitreal injection.
AbstractList Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a retrospective study, consecutive wide-field angiographs using the Heidelberg Retina Angiograph 2 with a contact lens system Staurenghi and SD-OCT were performed in diabetic patients with non proliferative diabetic retinopathy. Results A total of 71 eyes in 39 diabetic, average age was 58 years (SD 12). Most of the patients had type 2 diabetes mellitus (92%) and average duration since diabetes diagnosis was 10 years. Mean HA1c was 7.4%. Distribution of NPDR severity was: mild NPDR in 6% of eyes, moderate NPDR in 21% and severe NPDR in 73%. Macular edema was found in 53%. A thicker retina was observed in eyes with peripheral non perfusion (353 vs. 254 µm p = 0.006). Retinal non perfusion was associated with macular edema (97 vs. 76%, p = 0.01) and poor visual acuity (p < 0.001). Conclusions Diabetic macular edema seems to be strongly associated with peripheral retinal non perfusion. So treatment and management of diabetic macular edema may be reconsidered using either a targeted laser treatment in the area of retinal non perfusion or anti-VEGF intravitreal injection.
Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a retrospective study, consecutive wide‐field angiographs using the Heidelberg Retina Angiograph 2 with a contact lens system Staurenghi and SD‐OCT were performed in diabetic patients with non proliferative diabetic retinopathy. Results A total of 71 eyes in 39 diabetic, average age was 58 years (SD 12). Most of the patients had type 2 diabetes mellitus (92%) and average duration since diabetes diagnosis was 10 years. Mean HA1c was 7.4%. Distribution of NPDR severity was: mild NPDR in 6% of eyes, moderate NPDR in 21% and severe NPDR in 73%. Macular edema was found in 53%. A thicker retina was observed in eyes with peripheral non perfusion (353 vs. 254 μm p = 0.006). Retinal non perfusion was associated with macular edema (97 vs. 76%, p = 0.01) and poor visual acuity (p < 0.001). Conclusions Diabetic macular edema seems to be strongly associated with peripheral retinal non perfusion. So treatment and management of diabetic macular edema may be reconsidered using either a targeted laser treatment in the area of retinal non perfusion or anti‐VEGF intravitreal injection.
Abstract only
Author Maamouri, R.
Kort, F.
El Matri, K.
Bouraoui, R.
El Matri, L.
Falfoul, Y.
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Snippet Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a...
Abstract only
Purpose To evaluate diabetic macular edema in non proliferative diabetic retinopathy (NPDR) using a wide field fluorescein angiography. Methods In a...
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SubjectTerms Acuity
Angiography
Company reports
Diabetes
Diabetes mellitus
Diabetic retinopathy
Edema
Eye lens
Fluorescein
Medical imaging
Ophthalmology
Perfusion
Retina
Retinopathy
Vascular endothelial growth factor
Title Contribution of wide field angiography to diabetic macular edema
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