13 C hyperpolarization with nitrogen-vacancy centers in micro- and nanodiamonds for sensitive magnetic resonance applications
Nuclear hyperpolarization is a known method to enhance the signal in nuclear magnetic resonance (NMR) by orders of magnitude. The present work addresses the 13 C hyperpolarization in diamond micro- and nanoparticles, using the optically pumped nitrogen-vacancy center (NV) to polarize 13 C spins at r...
Saved in:
| Published in: | Science advances Vol. 11; no. 9; p. eadq6836 |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
28.02.2025
|
| ISSN: | 2375-2548, 2375-2548 |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Nuclear hyperpolarization is a known method to enhance the signal in nuclear magnetic resonance (NMR) by orders of magnitude. The present work addresses the 13 C hyperpolarization in diamond micro- and nanoparticles, using the optically pumped nitrogen-vacancy center (NV) to polarize 13 C spins at room temperature. Consequences of the small particle size are mitigated by using a combination of surface treatment improving the 13 C relaxation ( T 1 ) time, as well as that of NV, and applying a technique for NV illumination based on a microphotonic structure. Adjustments to the dynamical nuclear polarization sequence (PulsePol) are performed, as well as slow sample rotation, to improve the NV- 13 C polarization transfer rate. The hyperpolarized 13 C NMR signal is observed in particles of 2-micrometer and 100-nanometer median sizes, with enhancements over the thermal signal (at 0.29-tesla magnetic field) of 1500 and 940, respectively. The present demonstration of room-temperature hyperpolarization anticipates the development of agents based on nanoparticles for sensitive magnetic resonance applications.
Nuclear hyperpolarization of 13 C spins is performed at ambient conditions in micro- and nanodiamonds. |
|---|---|
| AbstractList | Nuclear hyperpolarization is a known method to enhance the signal in nuclear magnetic resonance (NMR) by orders of magnitude. The present work addresses the
C hyperpolarization in diamond micro- and nanoparticles, using the optically pumped nitrogen-vacancy center (NV) to polarize
C spins at room temperature. Consequences of the small particle size are mitigated by using a combination of surface treatment improving the
C relaxation (
) time, as well as that of NV, and applying a technique for NV illumination based on a microphotonic structure. Adjustments to the dynamical nuclear polarization sequence (PulsePol) are performed, as well as slow sample rotation, to improve the NV-
C polarization transfer rate. The hyperpolarized
C NMR signal is observed in particles of 2-micrometer and 100-nanometer median sizes, with enhancements over the thermal signal (at 0.29-tesla magnetic field) of 1500 and 940, respectively. The present demonstration of room-temperature hyperpolarization anticipates the development of agents based on nanoparticles for sensitive magnetic resonance applications. Nuclear hyperpolarization is a known method to enhance the signal in nuclear magnetic resonance (NMR) by orders of magnitude. The present work addresses the 13 C hyperpolarization in diamond micro- and nanoparticles, using the optically pumped nitrogen-vacancy center (NV) to polarize 13 C spins at room temperature. Consequences of the small particle size are mitigated by using a combination of surface treatment improving the 13 C relaxation ( T 1 ) time, as well as that of NV, and applying a technique for NV illumination based on a microphotonic structure. Adjustments to the dynamical nuclear polarization sequence (PulsePol) are performed, as well as slow sample rotation, to improve the NV- 13 C polarization transfer rate. The hyperpolarized 13 C NMR signal is observed in particles of 2-micrometer and 100-nanometer median sizes, with enhancements over the thermal signal (at 0.29-tesla magnetic field) of 1500 and 940, respectively. The present demonstration of room-temperature hyperpolarization anticipates the development of agents based on nanoparticles for sensitive magnetic resonance applications. Nuclear hyperpolarization of 13 C spins is performed at ambient conditions in micro- and nanodiamonds. |
| Author | Nothelfer, Steffen Knolle, Wolfgang Jentgens, Christian Jelezko, Fedor Plenio, Martin B. Blinder, Rémi Korzeczek, Martin Laube, Christian Mindarava, Yuliya Marshall, Alastair Glöckler, Felix Kienle, Alwin |
| Author_xml | – sequence: 1 givenname: Rémi orcidid: 0000-0001-6655-0150 surname: Blinder fullname: Blinder, Rémi organization: Institute for Quantum Optics, Albert-Einstein Allee 11, Ulm University, 89081 Ulm, Germany – sequence: 2 givenname: Yuliya orcidid: 0000-0003-3668-1672 surname: Mindarava fullname: Mindarava, Yuliya organization: Institute for Quantum Optics, Albert-Einstein Allee 11, Ulm University, 89081 Ulm, Germany – sequence: 3 givenname: Martin orcidid: 0000-0002-0349-374X surname: Korzeczek fullname: Korzeczek, Martin organization: Institute of Theoretical Physics, Albert-Einstein Allee 11, Ulm University, 89081 Ulm, Germany – sequence: 4 givenname: Alastair orcidid: 0000-0001-7772-2173 surname: Marshall fullname: Marshall, Alastair organization: NVision Imaging Technologies GmbH, 89081 Ulm, Germany – sequence: 5 givenname: Felix surname: Glöckler fullname: Glöckler, Felix organization: Institute for Laser Technologies in Medicine and Metrology at the University of Ulm (ILM), Helmholtzstr. 12, 89081 Ulm, Germany – sequence: 6 givenname: Steffen surname: Nothelfer fullname: Nothelfer, Steffen organization: Institute for Laser Technologies in Medicine and Metrology at the University of Ulm (ILM), Helmholtzstr. 12, 89081 Ulm, Germany – sequence: 7 givenname: Alwin surname: Kienle fullname: Kienle, Alwin organization: Institute for Laser Technologies in Medicine and Metrology at the University of Ulm (ILM), Helmholtzstr. 12, 89081 Ulm, Germany – sequence: 8 givenname: Christian orcidid: 0000-0002-6285-6934 surname: Laube fullname: Laube, Christian organization: Leibniz Institute of Surface Engineering, 04318 Leipzig, Germany – sequence: 9 givenname: Wolfgang orcidid: 0000-0003-4455-6898 surname: Knolle fullname: Knolle, Wolfgang organization: Leibniz Institute of Surface Engineering, 04318 Leipzig, Germany – sequence: 10 givenname: Christian orcidid: 0009-0007-2136-9252 surname: Jentgens fullname: Jentgens, Christian organization: Pureon AG, Kreuzlingerstrasse 1, 8574 Lengwil, Switzerland – sequence: 11 givenname: Martin B. orcidid: 0000-0003-4238-8843 surname: Plenio fullname: Plenio, Martin B. organization: Institute of Theoretical Physics, Albert-Einstein Allee 11, Ulm University, 89081 Ulm, Germany., Centre for Integrated Quantum Science and Technology (IQST), 89081 Ulm, Germany – sequence: 12 givenname: Fedor orcidid: 0000-0001-5759-3917 surname: Jelezko fullname: Jelezko, Fedor organization: Institute for Quantum Optics, Albert-Einstein Allee 11, Ulm University, 89081 Ulm, Germany., Centre for Integrated Quantum Science and Technology (IQST), 89081 Ulm, Germany |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/40020059$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kE1LAzEQhoNUbK29epT8ga1Jdje7e5TiFxS86HmZJpM20k3WZK1U8L-7tlVE8DRzeN4Z3ueUDJx3SMg5Z1POhbyMyoLeTEG_yDKVR2Qk0iJPRJ6Vg1_7kExifGaM8UzKnFcnZJgxJhjLqxH54Cmd0dW2xdD6NQT7Dp31jr7ZbkWd7YJfoks2oMCpLVXoOgyRWkcbq4JPKDhNHTivLTTe6UiNDzSii7azG6QNLB12VtGA0fecQgptu7Zq9yWekWMD64iTwxyTp5vrx9ldMn-4vZ9dzRPFs0ImkGpRlcYoLQXLOTcFSiwWJTAtMpNrkRqthDKYV4qXqFkBaVVobiQYIxeQjsnF_m77umhQ122wDYRt_e2hB6Z7oC8VY0Dzg3BWf7mu967rg-s-kP0JKNvtSnUB7Pq_2CeIDYml |
| CitedBy_id | crossref_primary_10_1002_wnan_70012 crossref_primary_10_1038_s43246_025_00840_0 crossref_primary_10_1103_PhysRevA_111_042432 crossref_primary_10_1063_5_0252743 crossref_primary_10_1021_acs_jpcc_5c02747 |
| Cites_doi | 10.1016/bs.mie.2018.08.016 10.1038/s41598-017-08709-0 10.1021/mp800051m 10.1103/PhysRevB.105.205401 10.1148/radiol.2019182391 10.1016/j.carbon.2020.04.071 10.1103/PhysRevB.92.184420 10.1103/PhysRevA.103.012607 10.1016/j.carbon.2020.07.077 10.1002/chem.201405253 10.1039/C7QM00241F 10.1103/PhysRevLett.106.157601 10.1088/1367-2630/18/1/013011 10.1016/j.cbpa.2023.102307 10.1063/1.477009 10.1103/PhysRevApplied.18.034079 10.1103/PhysRevB.100.041203 10.1103/PhysRevLett.131.010802 10.1088/1367-2630/18/1/013040 10.1016/j.jmr.2012.09.013 10.1016/j.carbon.2020.04.095 10.1088/0953-8984/27/7/072203 10.1016/j.jmr.2005.08.013 10.1016/j.jmr.2017.11.007 10.1038/s41467-019-13042-3 10.1021/acs.jpclett.1c00294 10.1103/PhysRevB.96.174436 10.1073/pnas.1733835100 10.1063/1.1746878 10.1103/PhysRevB.84.125406 10.1021/jacs.1c12442 10.1016/j.ssnmr.2021.101763 10.1126/scitranslmed.3006070 10.1103/PhysRevLett.121.246402 10.1088/1367-2630/14/10/103033 10.1021/acs.chemrev.2c00534 10.1103/PhysRevLett.104.070801 10.1038/s41598-019-42373-w 10.1002/cphc.201600301 10.1126/sciadv.aar5492 10.1021/acs.jpcc.2c06145 10.1021/jacs.2c07518 10.1016/j.ssnmr.2019.05.009 10.1038/nnano.2011.209 10.1002/qute.202000050 10.1016/j.diamond.2016.12.009 10.1016/S0079-6565(00)00025-X 10.3390/nano12244471 10.1021/jacs.9b03651 10.1021/jacs.1c09119 10.5194/mr-2-33-2021 10.1103/PhysRevLett.111.067601 10.1073/pnas.1807125115 10.1103/PhysRevB.91.165201 10.1016/B978-0-12-814024-6.00005-4 10.1126/sciadv.aat8978 10.1088/0034-4885/41/8/002 10.1038/ncomms9965 10.1016/0009-2614(90)87002-9 10.1063/1.5085351 10.1103/PhysRevB.101.155416 10.1021/acs.jpcc.1c08283 10.1021/ac201500v 10.1103/PhysRevB.79.075203 10.1016/0730-725X(85)90352-2 10.1103/PhysRevApplied.20.014040 10.1016/j.cobme.2019.03.002 10.1103/PhysRevLett.112.147602 10.1021/acs.jpcc.9b04110 |
| ContentType | Journal Article |
| DBID | AAYXX CITATION NPM |
| DOI | 10.1126/sciadv.adq6836 |
| DatabaseName | CrossRef PubMed |
| DatabaseTitle | CrossRef PubMed |
| DatabaseTitleList | PubMed CrossRef |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Sciences (General) |
| EISSN | 2375-2548 |
| ExternalDocumentID | 40020059 10_1126_sciadv_adq6836 |
| Genre | Journal Article |
| GroupedDBID | 53G 5VS AAFWJ AAYXX ACGFS ADAXU ADBBV ADPDF AENVI AFPKN ALMA_UNASSIGNED_HOLDINGS AOIJS BCGUY BCNDV BKF CITATION EBS FRP GROUPED_DOAJ GX1 HYE KQ8 M48 M~E OK1 OVD OVEED RHI RPM TEORI NPM |
| ID | FETCH-LOGICAL-c1476-a3d298ffcd620511f7e6e7b8a0d24f5d23fdc2cfe59c18ed07a397d1f6aff6ba3 |
| ISSN | 2375-2548 |
| IngestDate | Mon Jul 21 05:55:42 EDT 2025 Tue Nov 18 21:29:31 EST 2025 Sat Nov 29 08:12:42 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 9 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c1476-a3d298ffcd620511f7e6e7b8a0d24f5d23fdc2cfe59c18ed07a397d1f6aff6ba3 |
| ORCID | 0000-0002-6285-6934 0000-0003-4455-6898 0000-0001-6655-0150 0000-0003-4238-8843 0000-0003-3668-1672 0009-0007-2136-9252 0000-0001-7772-2173 0000-0002-0349-374X 0000-0001-5759-3917 |
| OpenAccessLink | https://www.science.org/doi/pdf/10.1126/sciadv.adq6836?download=true |
| PMID | 40020059 |
| ParticipantIDs | pubmed_primary_40020059 crossref_primary_10_1126_sciadv_adq6836 crossref_citationtrail_10_1126_sciadv_adq6836 |
| PublicationCentury | 2000 |
| PublicationDate | 2025-02-28 2025-Feb-28 |
| PublicationDateYYYYMMDD | 2025-02-28 |
| PublicationDate_xml | – month: 02 year: 2025 text: 2025-02-28 day: 28 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Science advances |
| PublicationTitleAlternate | Sci Adv |
| PublicationYear | 2025 |
| References | e_1_3_2_26_2 e_1_3_2_49_2 e_1_3_2_28_2 e_1_3_2_41_2 e_1_3_2_64_2 e_1_3_2_20_2 e_1_3_2_43_2 e_1_3_2_62_2 e_1_3_2_22_2 e_1_3_2_45_2 e_1_3_2_68_2 e_1_3_2_24_2 e_1_3_2_47_2 e_1_3_2_66_2 e_1_3_2_60_2 Shaka A. (e_1_3_2_57_2) 1987; 71 Yavkin B. V. (e_1_3_2_29_2) 2015; 17 e_1_3_2_9_2 e_1_3_2_16_2 e_1_3_2_37_2 e_1_3_2_7_2 e_1_3_2_18_2 e_1_3_2_39_2 e_1_3_2_54_2 e_1_3_2_75_2 e_1_3_2_10_2 e_1_3_2_31_2 e_1_3_2_52_2 e_1_3_2_73_2 e_1_3_2_5_2 e_1_3_2_12_2 e_1_3_2_33_2 e_1_3_2_58_2 e_1_3_2_3_2 e_1_3_2_35_2 e_1_3_2_56_2 e_1_3_2_50_2 e_1_3_2_71_2 e_1_3_2_27_2 e_1_3_2_48_2 e_1_3_2_40_2 e_1_3_2_65_2 e_1_3_2_21_2 e_1_3_2_42_2 e_1_3_2_63_2 Negoro M. (e_1_3_2_14_2) 2018; 122 e_1_3_2_23_2 e_1_3_2_44_2 e_1_3_2_69_2 e_1_3_2_25_2 e_1_3_2_46_2 e_1_3_2_67_2 e_1_3_2_61_2 e_1_3_2_15_2 e_1_3_2_38_2 e_1_3_2_8_2 e_1_3_2_17_2 e_1_3_2_59_2 e_1_3_2_6_2 e_1_3_2_19_2 e_1_3_2_30_2 e_1_3_2_53_2 e_1_3_2_32_2 e_1_3_2_51_2 e_1_3_2_74_2 e_1_3_2_11_2 e_1_3_2_34_2 e_1_3_2_4_2 e_1_3_2_13_2 e_1_3_2_36_2 e_1_3_2_55_2 e_1_3_2_2_2 e_1_3_2_72_2 e_1_3_2_70_2 |
| References_xml | – ident: e_1_3_2_6_2 doi: 10.1016/bs.mie.2018.08.016 – ident: e_1_3_2_21_2 doi: 10.1038/s41598-017-08709-0 – ident: e_1_3_2_18_2 doi: 10.1021/mp800051m – ident: e_1_3_2_64_2 doi: 10.1103/PhysRevB.105.205401 – ident: e_1_3_2_4_2 doi: 10.1148/radiol.2019182391 – ident: e_1_3_2_49_2 doi: 10.1016/j.carbon.2020.04.071 – ident: e_1_3_2_53_2 doi: 10.1103/PhysRevB.92.184420 – ident: e_1_3_2_52_2 doi: 10.1103/PhysRevA.103.012607 – ident: e_1_3_2_42_2 doi: 10.1016/j.carbon.2020.07.077 – ident: e_1_3_2_3_2 doi: 10.1002/chem.201405253 – ident: e_1_3_2_43_2 doi: 10.1039/C7QM00241F – ident: e_1_3_2_40_2 doi: 10.1103/PhysRevLett.106.157601 – ident: e_1_3_2_48_2 doi: 10.1088/1367-2630/18/1/013011 – ident: e_1_3_2_5_2 doi: 10.1016/j.cbpa.2023.102307 – ident: e_1_3_2_26_2 doi: 10.1063/1.477009 – ident: e_1_3_2_61_2 doi: 10.1103/PhysRevApplied.18.034079 – ident: e_1_3_2_36_2 doi: 10.1103/PhysRevB.100.041203 – volume: 17 start-page: 15101 year: 2015 ident: e_1_3_2_29_2 article-title: Size-dependent concentration of N0 paramagnetic centres in HPHT nanodiamonds publication-title: Magn. Reson. Solids – ident: e_1_3_2_58_2 doi: 10.1103/PhysRevLett.131.010802 – ident: e_1_3_2_35_2 doi: 10.1088/1367-2630/18/1/013040 – ident: e_1_3_2_73_2 doi: 10.1016/j.jmr.2012.09.013 – ident: e_1_3_2_45_2 doi: 10.1016/j.carbon.2020.04.095 – ident: e_1_3_2_44_2 doi: 10.1088/0953-8984/27/7/072203 – ident: e_1_3_2_69_2 doi: 10.1016/j.jmr.2005.08.013 – volume: 122 start-page: 4294 year: 2018 ident: e_1_3_2_14_2 article-title: Dissolution dynamic nuclear polarization at room temperature using photoexcited triplet electrons publication-title: Chem. A Eur. J. – ident: e_1_3_2_19_2 doi: 10.1016/j.jmr.2017.11.007 – ident: e_1_3_2_60_2 doi: 10.1038/s41467-019-13042-3 – ident: e_1_3_2_15_2 doi: 10.1021/acs.jpclett.1c00294 – ident: e_1_3_2_54_2 doi: 10.1103/PhysRevB.96.174436 – ident: e_1_3_2_11_2 doi: 10.1073/pnas.1733835100 – ident: e_1_3_2_50_2 doi: 10.1063/1.1746878 – ident: e_1_3_2_66_2 doi: 10.1103/PhysRevB.84.125406 – ident: e_1_3_2_7_2 doi: 10.1021/jacs.1c12442 – ident: e_1_3_2_10_2 doi: 10.1016/j.ssnmr.2021.101763 – ident: e_1_3_2_12_2 doi: 10.1126/scitranslmed.3006070 – ident: e_1_3_2_70_2 doi: 10.1103/PhysRevLett.121.246402 – ident: e_1_3_2_68_2 doi: 10.1088/1367-2630/14/10/103033 – ident: e_1_3_2_2_2 doi: 10.1021/acs.chemrev.2c00534 – ident: e_1_3_2_47_2 doi: 10.1103/PhysRevLett.104.070801 – ident: e_1_3_2_20_2 doi: 10.1038/s41598-019-42373-w – ident: e_1_3_2_27_2 doi: 10.1002/cphc.201600301 – ident: e_1_3_2_37_2 doi: 10.1126/sciadv.aar5492 – ident: e_1_3_2_28_2 doi: 10.1021/acs.jpcc.2c06145 – ident: e_1_3_2_17_2 doi: 10.1021/jacs.2c07518 – ident: e_1_3_2_9_2 doi: 10.1016/j.ssnmr.2019.05.009 – ident: e_1_3_2_24_2 doi: 10.1038/nnano.2011.209 – ident: e_1_3_2_39_2 doi: 10.1002/qute.202000050 – ident: e_1_3_2_59_2 – ident: e_1_3_2_55_2 doi: 10.1016/j.diamond.2016.12.009 – ident: e_1_3_2_22_2 doi: 10.1016/S0079-6565(00)00025-X – ident: e_1_3_2_63_2 doi: 10.3390/nano12244471 – ident: e_1_3_2_8_2 doi: 10.1021/jacs.9b03651 – ident: e_1_3_2_16_2 doi: 10.1021/jacs.1c09119 – ident: e_1_3_2_38_2 doi: 10.5194/mr-2-33-2021 – volume: 71 start-page: 495 year: 1987 ident: e_1_3_2_57_2 article-title: Symmetric phase-alternating composite pulses publication-title: J. Magn. Reson. – ident: e_1_3_2_75_2 – ident: e_1_3_2_33_2 doi: 10.1103/PhysRevLett.111.067601 – ident: e_1_3_2_74_2 doi: 10.1073/pnas.1807125115 – ident: e_1_3_2_67_2 doi: 10.1103/PhysRevB.91.165201 – ident: e_1_3_2_51_2 doi: 10.1016/B978-0-12-814024-6.00005-4 – ident: e_1_3_2_41_2 doi: 10.1126/sciadv.aat8978 – ident: e_1_3_2_25_2 doi: 10.1088/0034-4885/41/8/002 – ident: e_1_3_2_34_2 doi: 10.1038/ncomms9965 – ident: e_1_3_2_13_2 doi: 10.1016/0009-2614(90)87002-9 – ident: e_1_3_2_30_2 doi: 10.1063/1.5085351 – ident: e_1_3_2_32_2 doi: 10.1103/PhysRevB.101.155416 – ident: e_1_3_2_62_2 doi: 10.1021/acs.jpcc.1c08283 – ident: e_1_3_2_71_2 doi: 10.1021/ac201500v – ident: e_1_3_2_56_2 doi: 10.1103/PhysRevB.79.075203 – ident: e_1_3_2_72_2 doi: 10.1016/0730-725X(85)90352-2 – ident: e_1_3_2_65_2 doi: 10.1103/PhysRevApplied.20.014040 – ident: e_1_3_2_23_2 doi: 10.1016/j.cobme.2019.03.002 – ident: e_1_3_2_46_2 doi: 10.1103/PhysRevLett.112.147602 – ident: e_1_3_2_31_2 doi: 10.1021/acs.jpcc.9b04110 |
| SSID | ssj0001466519 |
| Score | 2.2840548 |
| Snippet | Nuclear hyperpolarization is a known method to enhance the signal in nuclear magnetic resonance (NMR) by orders of magnitude. The present work addresses the 13... Nuclear hyperpolarization is a known method to enhance the signal in nuclear magnetic resonance (NMR) by orders of magnitude. The present work addresses the C... |
| SourceID | pubmed crossref |
| SourceType | Index Database Enrichment Source |
| StartPage | eadq6836 |
| Title | 13 C hyperpolarization with nitrogen-vacancy centers in micro- and nanodiamonds for sensitive magnetic resonance applications |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/40020059 |
| Volume | 11 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 2375-2548 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001466519 issn: 2375-2548 databaseCode: DOA dateStart: 20150101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 2375-2548 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001466519 issn: 2375-2548 databaseCode: M~E dateStart: 20150101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELaWwoELojzLo_IBCVBktHEcOzmiFQgJqDgUVE4rxw8asZtdsu2qVIL_w79k_EialkUqBy7RyrItZ-fLeGY88xmhJ2bM9JhXBalKxQmjmhEJ0IDvqrK6sFnFPF3Tp3dib684OCg_jEa_ulqY9Uw0TXFyUi7_q6ihDYTtSmf_Qdz9pNAAv0Ho8ASxw_NSgk-zZJIcgnvZLp3bGussQ8AVvt92ASPJWiqnVhOXm-lKeOsmmbvUPOIPExrZLAA3sGTt6RqSlUtz90lGc_mlMYH32Rnxvt5gcAY-tHU7tRHTDM7i8TNH0RjyusM5_bzu5e5CBK1ce5P28_Gs_t5vG28X7alRp-ZrLDHqOMMDF8LKXQoTKnakKwlrh-EMOiwP91qPZiIn4LWGJrOhrVPb6QCe5ebdoLu_El70hdTfeJFtoN2-sB32SYrePaJ8GsZP4_gr6CoVeekU6Pufg3Ae4zz318j0i40UobFEa7CEcybQOWfGGzX7N9GN6I3glwFF22hkmltoOwpuhZ9FUvLnt9GPNMMT_AessIMVvggrHGGF6wYHWGGAFR7CCgOscA8r3MEK97DCQ1jdQR9fv9qfvCHx6g6iUiY4kZmmZWGt0pyC2k-tMNyIqpBjTZnNNc2sVlRZk5cqLYweCwmGsU4tl9bySmZ30VazaMx9hHmhlcgE7DVUsVS5g3FTwXxjZkDNKLaDSPdvTlXktXfXq8ymmwW4g572_ZeB0eWvPe8F4fT93CJcufaDS8_xEF0_Q_kjtHXUHpvH6JpaH9WrdtdHgHY9kn4DdJmtbg |
| linkProvider | ISSN International Centre |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=13+C+hyperpolarization+with+nitrogen-vacancy+centers+in+micro-+and+nanodiamonds+for+sensitive+magnetic+resonance+applications&rft.jtitle=Science+advances&rft.au=Blinder%2C+R%C3%A9mi&rft.au=Mindarava%2C+Yuliya&rft.au=Korzeczek%2C+Martin&rft.au=Marshall%2C+Alastair&rft.date=2025-02-28&rft.issn=2375-2548&rft.eissn=2375-2548&rft.volume=11&rft.issue=9&rft_id=info:doi/10.1126%2Fsciadv.adq6836&rft.externalDBID=n%2Fa&rft.externalDocID=10_1126_sciadv_adq6836 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2375-2548&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2375-2548&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2375-2548&client=summon |