Pathology of the gastrointestinal tract in overweight and obese children
Obesity and diseases of the gastrointestinal tract are widespread among the children and have common developmental mechanisms. The article provides a literature review on the relationships between certain pathological conditions of the digestive system (gastroesophageal reflux disease, gastritis, fu...
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| Vydáno v: | Sibirskiĭ nauchnyĭ medit︠s︡inskiĭ zhurnal Ročník 44; číslo 2; s. 28 - 38 |
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| Hlavní autoři: | , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina ruština |
| Vydáno: |
Russian Academy of Sciences, Siberian Branch Publishing House
26.04.2024
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| Témata: | |
| ISSN: | 2410-2512, 2410-2520 |
| On-line přístup: | Získat plný text |
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| Shrnutí: | Obesity and diseases of the gastrointestinal tract are widespread among the children and have common developmental mechanisms. The article provides a literature review on the relationships between certain pathological conditions of the digestive system (gastroesophageal reflux disease, gastritis, functional intestinal disorders, Crohn’s disease, diverticular disease) in children with overweight and obesity. Excess body weight and obesity can become risk factors for the development of gastrointestinal pathology. The data available in modern literature on changes in the composition of the intestinal and stomach microbiocenosis with increasing body weight are summarized (changes in enterotype, increase in the
Firmicutеs/Bacteroides
ratio, increase in the number of bacteria
Methanobrevibacter, Escherichia coli, Lactobacillus rhamnosus, Lactobacillus delbrueckii and Lactobacillus reuteri
). The strains of bacteria that contribute to the anorexigenic effect are considered:
Lactobacillus gasseri
, some strains of
Bifidobacterium
,
Saccharomyce
s,
Streptococcus
and
Enterococcus
. The pathogenetic aspects of obesity and overweight caused by microbiota are presented: activation of lipid synthesis, breakdown of polysaccharides, absorption of mono- and disaccharides, development of metabolic endotoxemia, etc. Features of the functioning of the autonomic nervous system in obesity in children are presented, indicating the predominance of the hypersympathicotonic variant of autonomic reactivity. |
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| ISSN: | 2410-2512 2410-2520 |
| DOI: | 10.18699/SSMJ20240203 |