SS – OCT angiography in macular dystrophies
Purpose To assess the ability of swept source optical coherence tomography angiography (SS – OCT‐A) to identify abnormalities of the retinal and choroidal vascular network in macular dystrophies. Methods Optical coherence tomography angiography and structural OCT were performed using a Swept‐source...
Saved in:
| Published in: | Acta ophthalmologica (Oxford, England) Vol. 95; no. S259 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Malden
Wiley Subscription Services, Inc
01.09.2017
|
| Subjects: | |
| ISSN: | 1755-375X, 1755-3768 |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Purpose
To assess the ability of swept source optical coherence tomography angiography (SS – OCT‐A) to identify abnormalities of the retinal and choroidal vascular network in macular dystrophies.
Methods
Optical coherence tomography angiography and structural OCT were performed using a Swept‐source DRI OCT Triton (Topcon, Corporation, Japan) for patients with Stargardt disease, Best maculopathy, pseudo‐vitelliform dystrophy and progressive cone dystrophy. In our series, for every patient the clinical diagnosis was confirmed by the results of molecular genetic study.
Results
In Stargardt patients, we found alterations especially located at the level of the deep capillary plexus and choriocapillaris. There were different degrees of choriocapillaris impairment, with no residual choriocapillaris inside area of retinal epithelium pigment atrophy in advanced stages. Large choroidal vessels and borders of the atrophy were well visualized. In patients with Best maculopathy and pseudo‐vitelliform dystrophy, OCT‐A revealed neovascularisation in the outer retina and the choriocapillaris while traditional multimodal imaging wasn't conclusive. In progressive cone dystrophy, there was a retinal vasculature signal reduction in both superficial and deep plexus associated with window effect in the outer retina and the choriocapillaris due to the retinal and RPE atrophy.
Conclusions
In inherited macular distrophies, OCT‐A may provide information of great interest. In stargardt disease, OCT‐A findings were in agreement with the results suggesting primitive severe involvement of choriocapillaris. In Best maculopathy and pseudo‐witelliform dystrophies, OCT‐A helps diagnose choroidal neovascularization. In Progressive cone dystrophies, it could be useful for gaining deeper Knowledge of both the pathogenesis and therapeutic implications. |
|---|---|
| AbstractList | Abstract only Purpose To assess the ability of swept source optical coherence tomography angiography (SS – OCT‐A) to identify abnormalities of the retinal and choroidal vascular network in macular dystrophies. Methods Optical coherence tomography angiography and structural OCT were performed using a Swept‐source DRI OCT Triton (Topcon, Corporation, Japan) for patients with Stargardt disease, Best maculopathy, pseudo‐vitelliform dystrophy and progressive cone dystrophy. In our series, for every patient the clinical diagnosis was confirmed by the results of molecular genetic study. Results In Stargardt patients, we found alterations especially located at the level of the deep capillary plexus and choriocapillaris. There were different degrees of choriocapillaris impairment, with no residual choriocapillaris inside area of retinal epithelium pigment atrophy in advanced stages. Large choroidal vessels and borders of the atrophy were well visualized. In patients with Best maculopathy and pseudo‐vitelliform dystrophy, OCT‐A revealed neovascularisation in the outer retina and the choriocapillaris while traditional multimodal imaging wasn't conclusive. In progressive cone dystrophy, there was a retinal vasculature signal reduction in both superficial and deep plexus associated with window effect in the outer retina and the choriocapillaris due to the retinal and RPE atrophy. Conclusions In inherited macular distrophies, OCT‐A may provide information of great interest. In stargardt disease, OCT‐A findings were in agreement with the results suggesting primitive severe involvement of choriocapillaris. In Best maculopathy and pseudo‐witelliform dystrophies, OCT‐A helps diagnose choroidal neovascularization. In Progressive cone dystrophies, it could be useful for gaining deeper Knowledge of both the pathogenesis and therapeutic implications. Purpose To assess the ability of swept source optical coherence tomography angiography (SS - OCT-A) to identify abnormalities of the retinal and choroidal vascular network in macular dystrophies. Methods Optical coherence tomography angiography and structural OCT were performed using a Swept-source DRI OCT Triton (Topcon, Corporation, Japan) for patients with Stargardt disease, Best maculopathy, pseudo-vitelliform dystrophy and progressive cone dystrophy. In our series, for every patient the clinical diagnosis was confirmed by the results of molecular genetic study. Results In Stargardt patients, we found alterations especially located at the level of the deep capillary plexus and choriocapillaris. There were different degrees of choriocapillaris impairment, with no residual choriocapillaris inside area of retinal epithelium pigment atrophy in advanced stages. Large choroidal vessels and borders of the atrophy were well visualized. In patients with Best maculopathy and pseudo-vitelliform dystrophy, OCT-A revealed neovascularisation in the outer retina and the choriocapillaris while traditional multimodal imaging wasn't conclusive. In progressive cone dystrophy, there was a retinal vasculature signal reduction in both superficial and deep plexus associated with window effect in the outer retina and the choriocapillaris due to the retinal and RPE atrophy. Conclusions In inherited macular distrophies, OCT-A may provide information of great interest. In stargardt disease, OCT-A findings were in agreement with the results suggesting primitive severe involvement of choriocapillaris. In Best maculopathy and pseudo-witelliform dystrophies, OCT-A helps diagnose choroidal neovascularization. In Progressive cone dystrophies, it could be useful for gaining deeper Knowledge of both the pathogenesis and therapeutic implications. |
| Author | Maamouri, R. Chebil, A. El Matri, K. El Matri, L. Falfoul, Y. Hassairi, A. |
| Author_xml | – sequence: 1 givenname: L. surname: El Matri fullname: El Matri, L. organization: Institut Hedi Rais of Ophthalmology – sequence: 2 givenname: Y. surname: Falfoul fullname: Falfoul, Y. organization: Institut Hedi Rais of Ophthalmology – sequence: 3 givenname: K. surname: El Matri fullname: El Matri, K. organization: Institut Hedi Rais of Ophthalmology – sequence: 4 givenname: A. surname: Hassairi fullname: Hassairi, A. organization: Institut Hedi Rais of Ophthalmology – sequence: 5 givenname: R. surname: Maamouri fullname: Maamouri, R. organization: Institut Hedi Rais of Ophthalmology – sequence: 6 givenname: A. surname: Chebil fullname: Chebil, A. organization: Institut Hedi Rais of Ophthalmology |
| BookMark | eNqNkM1Kw0AQxxdRsK2-ggQ8J85-ZJMFL6VYFQo9tIK3Zd1M2oQ2ibstkpvv4Bv6JCZGenYuMwz_33z8x-S8qisk5IZCRLu4KyOaxHHIE5lGDGgSwRwoOyOjU_v8VMevl2TsfQkgqZRiRMLVKvj-_AqWs3Vgqk1Rb5xptm1QVMHe2OPOuCBr_cHVzbZAf0UucrPzeP2XJ-Rl_rCePYWL5ePzbLoILWUpCwUKqiznWSZsklqkb8KalDFQENMYIAaboRJoEbiCLEHZ3Q0ikzkHhbniE3I7zG1c_X5Ef9BlfXRVt1JTxSXjQtKkU8lBZV3tvcNcN67YG9dqCrq3Rpe6_1v3HujeGv1rTQfeD-BHscP2n5SeLlcD_gNZ72jr |
| ContentType | Journal Article |
| Copyright | 2017 The Authors Acta Ophthalmologica © 2017 Acta Ophthalmologica Scandinavica Foundation Copyright © 2017 Acta Ophthalmologica Scandinavica Foundation |
| Copyright_xml | – notice: 2017 The Authors Acta Ophthalmologica © 2017 Acta Ophthalmologica Scandinavica Foundation – notice: Copyright © 2017 Acta Ophthalmologica Scandinavica Foundation |
| DBID | AAYXX CITATION 7TK |
| DOI | 10.1111/j.1755-3768.2017.0F012 |
| DatabaseName | CrossRef Neurosciences Abstracts |
| DatabaseTitle | CrossRef Neurosciences Abstracts |
| DatabaseTitleList | CrossRef Neurosciences Abstracts |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1755-3768 |
| EndPage | n/a |
| ExternalDocumentID | 10_1111_j_1755_3768_2017_0F012 AOS0F012 |
| Genre | abstract |
| GroupedDBID | --- .3N .55 .GA .Y3 05W 0R~ 10A 1OB 1OC 23M 31~ 33P 36B 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5HH 5LA 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAESR AAEVG AAHQN AAIPD AAMMB AAMNL AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCUV ABDBF ABEML ABJNI ABPVW ABQWH ABXGK ACAHQ ACCZN ACGFS ACGOF ACMXC ACNCT ACPOU ACPRK ACSCC ACUHS ACXBN ACXQS ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADOZA ADXAS ADZMN AEFGJ AEIGN AEIMD AENEX AEUYR AEYWJ AFBPY AFFPM AFGKR AFRAH AFWVQ AFZJQ AGHNM AGXDD AGYGG AHBTC AHMBA AIACR AIDQK AIDYY AITYG AIURR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BAWUL BFHJK BHBCM BMXJE BROTX BRXPI BY8 C45 CAG COF CS3 D-6 D-7 D-E D-F DCZOG DIK DPXWK DR2 DRFUL DRMAN DRSTM E3Z EAD EAP EBC EBD EBS EJD EMB EMK EMOBN ESX EX3 F00 F01 F04 F5P FIJ FUBAC G-S GODZA H.X HF~ HGLYW HZI HZ~ IX1 J0M K48 KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ O66 O9- OIG OVD P2W P2X P2Z P4B P4D P6G PQQKQ Q.N Q11 QB0 R.K RIWAO RJQFR ROL RX1 SUPJJ SV3 TEORI TR2 TUS UB1 V9Y W8V W99 WBKPD WHWMO WIH WIJ WIK WIN WOHZO WOW WQJ WVDHM WXI WXSBR X7M XG1 ~IA ~WT AAYXX CITATION O8X 7TK |
| ID | FETCH-LOGICAL-c1282-4e419c33dd4c78ce1b4ca8220905150050cde94ece0390d7e620104d6f309ef93 |
| IEDL.DBID | DRFUL |
| ISSN | 1755-375X |
| IngestDate | Sat Nov 29 15:03:36 EST 2025 Sat Nov 29 01:34:46 EST 2025 Sun Sep 21 06:12:39 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | S259 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c1282-4e419c33dd4c78ce1b4ca8220905150050cde94ece0390d7e620104d6f309ef93 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 |
| PQID | 1936234617 |
| PQPubID | 1036384 |
| PageCount | 1 |
| ParticipantIDs | proquest_journals_1936234617 crossref_primary_10_1111_j_1755_3768_2017_0F012 wiley_primary_10_1111_j_1755_3768_2017_0F012_AOS0F012 |
| PublicationCentury | 2000 |
| PublicationDate | September 2017 2017-09-00 20170901 |
| PublicationDateYYYYMMDD | 2017-09-01 |
| PublicationDate_xml | – month: 09 year: 2017 text: September 2017 |
| PublicationDecade | 2010 |
| PublicationPlace | Malden |
| PublicationPlace_xml | – name: Malden |
| PublicationTitle | Acta ophthalmologica (Oxford, England) |
| PublicationYear | 2017 |
| Publisher | Wiley Subscription Services, Inc |
| Publisher_xml | – name: Wiley Subscription Services, Inc |
| SSID | ssj0061664 |
| Score | 2.1542785 |
| Snippet | Purpose
To assess the ability of swept source optical coherence tomography angiography (SS – OCT‐A) to identify abnormalities of the retinal and choroidal... Abstract only Purpose To assess the ability of swept source optical coherence tomography angiography (SS - OCT-A) to identify abnormalities of the retinal and choroidal... |
| SourceID | proquest crossref wiley |
| SourceType | Aggregation Database Index Database Publisher |
| SubjectTerms | Angiography Atrophy Epithelium Medical imaging Retina Tomography Vascularization |
| Title | SS – OCT angiography in macular dystrophies |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1755-3768.2017.0F012 https://www.proquest.com/docview/1936234617 |
| Volume | 95 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVWIB databaseName: Wiley Online Library Free Content customDbUrl: eissn: 1755-3768 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0061664 issn: 1755-375X databaseCode: WIN dateStart: 20080101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell – providerCode: PRVWIB databaseName: Wiley Online Library Full Collection 2020 customDbUrl: eissn: 1755-3768 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0061664 issn: 1755-375X databaseCode: DRFUL dateStart: 20080101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3PT8IwFH5BMMaLv40okh28TsfWruuRoAsmCEYgclu6tlMODgJo4s3_wf_Qv8S22xTixRhvzZI2y5f3-r62730P4Iz6SFKBuW6TSmzkx8yOCQ9sj0nCPZcKjk2hcId0u8FoRG9L0C5qYTJ9iK8LN-0ZZr_WDs7i-aqTE4y1g5gMLXLuhI5uN1xxlRHjMlQu78Jhp9iV_YZvpKTyOXiUVwsXWT0_V1oNVN_sc5nDmiAUbv_f7-_AVk5ErWZmObtQkukebNzkT-37YPf71sfbu9VrDSyWPoxzaWtrnFpPzCSvWuJ1vphNpo_qsH0Aw_Bq0GrbeW8Fm6uI5NpIogblnicE4iTgshEjzhRZcLReF9aqMFxIiqRuJ0YdQaSvn82R8BPPoTKh3iGU00kqj8ASGMWBL1jSYDHyPMwSh7qBiv2KujFBUBUuCiCjaSahES0dPRQKkUYh0ihEBoUq1Aq8o9yl5pFimoqqIcW4qoANsr9cLWr2-mZw_Md5J7Cpv2aZZTUoL2bP8hTW-ctiPJ_Vc0Orw9r9dfcT8lzO4Q |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1NTwMhECWmGvXit7FalYPX1W2BZTk2jU0b261Ja-yNsMBqD26btpp48z_4D_0lArurbbwY440DEPLCMA-YeQPABQuwZopIWyaVejiIhRdTGXpIaCpRjSlJXKJwh0ZROByy21xSyObCZPoQXw9u1jLceW0N3D5IL1s5JcRaiAvRopd-07f1hlexYR22isN9OyoO5aAaOCWpfAQZ5snCRVDPz3mW_dQ3-VyksM4HNbf_cfU7YCsnorCe7ZxdsKLTPbDezb_a94HX78OPt3fYawygSB9GubQ1HKXwSbjgVaheZ_PpePJoLtsH4K55PWi0vLy2gieNR6p5WOMqkwgphSUNpa7GWApDFnyr10WsKoxUmmFty4kxX1Ed2G9zrIIE-UwnDB2CUjpO9RGAiuA4DJRIqiLGCBGR-KwWGt9vqJtQFJfBVYEkn2QSGnzh6mFQ4BYFblHgDoUyqBSA89ykZtwwTUPVsGFcZUActL-cjdd7fdc4_uO4c7DRGnQ7vNOObk7Apu2RRZlVQGk-fdanYE2-zEez6Znbc58pFtCU |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=SS+%E2%80%93+OCT+angiography+in+macular+dystrophies&rft.jtitle=Acta+ophthalmologica+%28Oxford%2C+England%29&rft.au=El+Matri%2C+L.&rft.au=Falfoul%2C+Y.&rft.au=El+Matri%2C+K.&rft.au=Hassairi%2C+A.&rft.date=2017-09-01&rft.issn=1755-375X&rft.eissn=1755-3768&rft.volume=95&rft.epage=n%2Fa&rft_id=info:doi/10.1111%2Fj.1755-3768.2017.0F012&rft.externalDBID=10.1111%252Fj.1755-3768.2017.0F012&rft.externalDocID=AOS0F012 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1755-375X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1755-375X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1755-375X&client=summon |