34Hypoxia and immune suppression shapes therapeutic outcomes and metastases in clear cell renal cell carcinoma

Abstract Background Vascular endothelial growth factor receptor-targeting tyrosine kinase inhibitors (VEGFR-TKIs) and aPD1 combinations are effective in multiple solid tumors, particularly in clear cell renal cell carcinoma (ccRCC), due to its characteristic pseudo-hypoxic, hyper-angiogenic state dr...

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Vydáno v:	The oncologist (Dayton, Ohio) Ročník 30; číslo Supplement_2
Hlavní autoři:	Vuong, Lynda, Cornish, Andrew, Khandwala, Yash, Jiang, Hui, Mascareno, Eduardo, Zheng, Doris, Rappold, Phillip, Leibold, Josef, Sabio, Erich, Weiss, Kate, Gonzalez, Carlene, Rittenhouse, Nicole, Ji, Liangliang, Zhang, Jing, Adlesic, Mojca, Akin, Oguz, Flynn, Jessica, Krishna, Chirag, Sanchez, Alejandro, Natale, Renzo Di, Blum, Kyle, Russo, Paul, Coleman, Jonathan, Frew, Ian, Chowell, Diego, Chen, Yingbei, Solit, David, Ostrovnaya, Irina, Motzer, Robert, Voss, Martin, Kotecha, Ritesh, Chan, Timothy, Kuo, Fengshen, Li, Ming, Hakimi, A Ari
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Oxford University Press 01.10.2025
Témata:	hypoxia tumor associated macrophages immune checkpoint blockade
ISSN:	1083-7159, 1549-490X
On-line přístup:	Získat plný text
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