34Hypoxia and immune suppression shapes therapeutic outcomes and metastases in clear cell renal cell carcinoma

Abstract Background Vascular endothelial growth factor receptor-targeting tyrosine kinase inhibitors (VEGFR-TKIs) and aPD1 combinations are effective in multiple solid tumors, particularly in clear cell renal cell carcinoma (ccRCC), due to its characteristic pseudo-hypoxic, hyper-angiogenic state dr...

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Vydané v:	The oncologist (Dayton, Ohio) Ročník 30; číslo Supplement_2
Hlavní autori:	Vuong, Lynda, Cornish, Andrew, Khandwala, Yash, Jiang, Hui, Mascareno, Eduardo, Zheng, Doris, Rappold, Phillip, Leibold, Josef, Sabio, Erich, Weiss, Kate, Gonzalez, Carlene, Rittenhouse, Nicole, Ji, Liangliang, Zhang, Jing, Adlesic, Mojca, Akin, Oguz, Flynn, Jessica, Krishna, Chirag, Sanchez, Alejandro, Natale, Renzo Di, Blum, Kyle, Russo, Paul, Coleman, Jonathan, Frew, Ian, Chowell, Diego, Chen, Yingbei, Solit, David, Ostrovnaya, Irina, Motzer, Robert, Voss, Martin, Kotecha, Ritesh, Chan, Timothy, Kuo, Fengshen, Li, Ming, Hakimi, A Ari
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Oxford University Press 01.10.2025
Predmet:	hypoxia tumor associated macrophages immune checkpoint blockade
ISSN:	1083-7159, 1549-490X
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