Front Cover: Process Monitoring of Lactone Ring Formation and Opening by Operando Attenuated Total Reflectance Infrared Spectroscopy (Chem. Methods 10/2025)

The Front Cover features a liquid‐phase hydrogenation reactor, employing attenuated total reflectance‐infrared (ATR‐IR), Raman, and fluorescence spectroscopy under industrially relevant conditions. Specifically, it highlights the use of inline ATR‐IR spectroscopy and partial least‐squares regression...

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Bibliographic Details
Published in:Chemistry methods Vol. 5; no. 10
Main Authors: Bos, Jelle W., de Peinder, Peter, Janssens, Joris C. L., Oord, Ramon, Monai, Matteo, Vogt, Eelco T. C., Weckhuysen, Bert M.
Format: Journal Article
Language:English
Published: 01.10.2025
ISSN:2628-9725, 2628-9725
Online Access:Get full text
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Summary:The Front Cover features a liquid‐phase hydrogenation reactor, employing attenuated total reflectance‐infrared (ATR‐IR), Raman, and fluorescence spectroscopy under industrially relevant conditions. Specifically, it highlights the use of inline ATR‐IR spectroscopy and partial least‐squares regression to determine the concentrations of two bio‐derived lactones from the acquired spectra. In the Research Article by B. M. Weckhuysen and co‐workers (DOI: 10.1002/cmtd.202500054), the reactor design is clarified, and changes in the spectra not induced by concentration changes are pinpointed, shedding light on the challenges associated with performing spectroscopy under reaction conditions.
ISSN:2628-9725
2628-9725
DOI:10.1002/cmtd.70042