ROLE OF SEROTONIN IN THE HUMAN BODY
The objective of this article is to review recent literature on the functions of serotonin in the human body, its metabolism, hormonal and mediator effects. The article reviews modern concepts of serotonin receptors and their main functions and localization in the central nervous system (CNS) and ga...
Gespeichert in:
| Veröffentlicht in: | Zhurnal Grodnenskogo gosudarstvennogo medit͡s︡inskogo universiteta Jg. 23; H. 4; S. 303 - 310 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
01.09.2025
|
| ISSN: | 2221-8785, 2413-0109 |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | The objective of this article is to review recent literature on the functions of serotonin in the human body, its metabolism, hormonal and mediator effects. The article reviews modern concepts of serotonin receptors and their main functions and localization in the central nervous system (CNS) and gastrointestinal tract (GIT). Imbalance of serotonergic neurons functions affects the development of CNS and GI pathologies. Peripheral serotonin plays an important role in the function of platelets, intestine and pancreas. Tryptophan hydroxylase type 2 inhibitors have shown therapeutic efficacy in GI diseases. |
|---|---|
| AbstractList | The objective of this article is to review recent literature on the functions of serotonin in the human body, its metabolism, hormonal and mediator effects. The article reviews modern concepts of serotonin receptors and their main functions and localization in the central nervous system (CNS) and gastrointestinal tract (GIT). Imbalance of serotonergic neurons functions affects the development of CNS and GI pathologies. Peripheral serotonin plays an important role in the function of platelets, intestine and pancreas. Tryptophan hydroxylase type 2 inhibitors have shown therapeutic efficacy in GI diseases. |
| Author | Zolotukhin, M. M. Smirnov, V. Yu Naumov, A. V. Doroshenko, Ye. M. |
| Author_xml | – sequence: 1 givenname: M. M. surname: Zolotukhin fullname: Zolotukhin, M. M. – sequence: 2 givenname: Ye. M. orcidid: 0000-0001-9939-8749 surname: Doroshenko fullname: Doroshenko, Ye. M. – sequence: 3 givenname: A. V. orcidid: 0000-0002-5459-783X surname: Naumov fullname: Naumov, A. V. – sequence: 4 givenname: V. Yu orcidid: 0000-0002-9162-0613 surname: Smirnov fullname: Smirnov, V. Yu |
| BookMark | eNo1z01Lw0AQBuBFKlhr_0NAr6sz-5HdBS-1pqYQs1Dbg6clO92Aoq0kJ_-9iVUY3pnD8MJzySaH4yExdoNwK7Rw9k4Igdwaq7kAMYTkikuQXCKcsalQKDkguMlw_39esHnfvwMAWpEbxCm73viqyPwqeyk2fuvrdZ0Nsy2LrNw9L-rswT--XrHztvno0_xvz9huVWyXJa_803q5qDghGOA6EimbTGOS2TuKwlAiqVWzj6gtSOesxai1jTFPZPI2z9Ea0ojWUUtKztj9qZe6Y993qQ1f3dtn030HhPBrDqMkjJIwmoOQQYXBHAaz_AEyT0cI |
| ContentType | Journal Article |
| CorporateAuthor | Grodno State Medical University, Grodno, Belarus |
| CorporateAuthor_xml | – name: Grodno State Medical University, Grodno, Belarus |
| DBID | AAYXX CITATION |
| DOI | 10.25298/2221-8785-2025-23-4-303-310 |
| DatabaseName | CrossRef |
| DatabaseTitle | CrossRef |
| DatabaseTitleList | CrossRef |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2413-0109 |
| EndPage | 310 |
| ExternalDocumentID | 10_25298_2221_8785_2025_23_4_303_310 |
| GroupedDBID | AAYXX ALMA_UNASSIGNED_HOLDINGS CITATION GROUPED_DOAJ VCL VIT |
| ID | FETCH-LOGICAL-c1070-5bcc48e7a7e7d9cb27cec354adb1580399881b558bb6ec76f66187c51189cfc43 |
| ISSN | 2221-8785 |
| IngestDate | Sat Nov 29 07:35:28 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c1070-5bcc48e7a7e7d9cb27cec354adb1580399881b558bb6ec76f66187c51189cfc43 |
| ORCID | 0000-0002-9162-0613 0000-0001-9939-8749 0000-0002-5459-783X |
| OpenAccessLink | http://journal-grsmu.by/index.php/ojs/article/download/3310/2923 |
| PageCount | 8 |
| ParticipantIDs | crossref_primary_10_25298_2221_8785_2025_23_4_303_310 |
| PublicationCentury | 2000 |
| PublicationDate | 2025-09-00 |
| PublicationDateYYYYMMDD | 2025-09-01 |
| PublicationDate_xml | – month: 09 year: 2025 text: 2025-09-00 |
| PublicationDecade | 2020 |
| PublicationTitle | Zhurnal Grodnenskogo gosudarstvennogo medit͡s︡inskogo universiteta |
| PublicationYear | 2025 |
| SSID | ssj0001826711 |
| Score | 2.3017151 |
| Snippet | The objective of this article is to review recent literature on the functions of serotonin in the human body, its metabolism, hormonal and mediator effects.... |
| SourceID | crossref |
| SourceType | Index Database |
| StartPage | 303 |
| Title | ROLE OF SEROTONIN IN THE HUMAN BODY |
| Volume | 23 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 2413-0109 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001826711 issn: 2221-8785 databaseCode: DOA dateStart: 20030101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3da9swEBehG2MvY2Mb-8aw5sk484dUSY9pm6yD1h5tWtq-GFuWm5DVLokd-tftb9udv-r1YXSDgTDmnJxl3_HT_aQ7i5BtTlWcpDSxeKSYRbmiVqRix4plxHgUIVhWlj7kvi_Oz-X3weBnWwuz-cGzTNzeypv_amqQgbGxdPYvzN0pBQGcg9HhCGaH44MMfxwcTjCX52RyHMwC_5tvQsPEnoPTo7Fv7gb7v0Wkl_M6Iv0KSJoBp13mV7l5la_LBChvAVCYoQCX4Ivh3v5w7KyHk-lwV8DZovl12SZ36KID-UsA1aJczutPFByNoHUxcw4j81xny2qW9kL3r_lReZ1vKsAamWed-OR6scpq-dnIvCj7cxUu65KxGkiDYMQB_K036RnpWkZxfwnHln1MrmuQG9-jPYD1bK83Vnt1Suz9YcBlrsTahu52VtUZ17NwFQjrCe274a9d8r83Kna5isCSKn0hagtRW4jaQtcLaQjaQg8r_B65nEnZo_TVHB9wN15tAd315AnZbjv45Q_d60VJvXBn9pw8a3iKMa796wUZ6Owl-Yy-ZQRTo_MtAxr4llH5loG-9YqcTiezvQOr2WXDUkD9bYvFSlGhecQ1T6SKXa608hiNkthhwoYAVgC1YUzE8Y5WfCeFiE5whcxUqlRR7zXZyvJMvyEGF4kXw-VUIcu2lRSpI5NEcltEOP3xlrD2qcKb-mMq4UNe77t__N978vTOCz-QrWJV6o_ksdoUi_XqU2WrX5nTXyA |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=ROLE+OF+SEROTONIN+IN+THE+HUMAN+BODY&rft.jtitle=Zhurnal+Grodnenskogo+gosudarstvennogo+medit%CD%A1s%EF%B8%A1inskogo+universiteta&rft.au=Zolotukhin%2C+M.+M.&rft.au=Doroshenko%2C+Ye.+M.&rft.au=Naumov%2C+A.+V.&rft.au=Smirnov%2C+V.+Yu&rft.date=2025-09-01&rft.issn=2221-8785&rft.eissn=2413-0109&rft.volume=23&rft.issue=4&rft.spage=303&rft.epage=310&rft_id=info:doi/10.25298%2F2221-8785-2025-23-4-303-310&rft.externalDBID=n%2Fa&rft.externalDocID=10_25298_2221_8785_2025_23_4_303_310 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2221-8785&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2221-8785&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2221-8785&client=summon |