Electrolyte Disturbances after Lumbar Interbody Fusion: A Comparison of Anterior/Lateral and Posterior Approaches
Background: Electrolyte disorders are uncommon but associated with adverse outcomes following lumbar spinal fusion. No previous study has examined rates of electrolyte disturbances after interbody fusions and compared them between anterior/lateral and posterior-based interbody fusions. The purpose o...
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| Vydané v: | Clinics in orthopedic surgery Ročník 17; číslo 6; s. 978 - 984 |
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| Hlavní autori: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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대한정형외과학회
01.12.2025
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| Abstract | Background: Electrolyte disorders are uncommon but associated with adverse outcomes following lumbar spinal fusion. No previous study has examined rates of electrolyte disturbances after interbody fusions and compared them between anterior/lateral and posterior-based interbody fusions. The purpose of this study is to identify the incidence of electrolyte disturbances following lumbar interbody fusion and compare the difference in incidence between anterior/lateral lumbar interbody fusions (ALIF/LLIF) and posterior/transforaminal lumbar interbody fusions (PLIF/TLIF).
Methods: A large multi-payer database was queried to identify patients who underwent ALIF/LLIF or PLIF/TLIF from 2010 to 2022.
The incidence of electrolyte abnormalities following each procedure was examined for up to 7 days postoperatively. The cohorts were matched 1 : 1 by demographics and comorbidities.
Results: Among 132,837 ALIF/LLIF and 492,129 PLIF/TLIF patients, the mean age was 60.18 years, 57.5% were female, and the mean Charlson Comorbidity Index was 1.76. There was a downward trend in the incidences of electrolyte abnormalities over the postoperative course except for hypercalcemia (anterior/lateral: p = 0.368; posterior: p = 0.764) and alkalosis (anterior/lateral: p = 0.764; posterior: p = 0.764) in both cohorts, as well as hypernatremia (p = 0.368) in the anterior/lateral cohort, in the first 7 days postoperatively. Patients with electrolyte abnormalities had higher rates of early postoperative ileus (5.84% vs. 1.26%), longer length of stay (9.22 vs. 6.08), higher rates of 90-day readmissions (17.30% vs. 4.48%), and higher costs ($19,946.70 vs. $15,190.87) (all p < 0.001). After matching, the anterior/lateral cohort had higher rates of hypokalemia (anterior = 1.19% vs. posterior = 1.00%, p < 0.001) and acidosis (0.25% vs. 0.18%, p < 0.001) than the posterior cohort.
Conclusions: Electrolyte disturbance following lumbar interbody fusion is associated with ileus, prolonged length of stay, and increased readmission rates and cost. Given the influence of electrolyte disturbances on postoperative outcomes, ongoing efforts to identify the prevalence and risk factors for electrolyte derangement in the perioperative period are warranted. KCI Citation Count: 0 |
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| AbstractList | Background: Electrolyte disorders are uncommon but associated with adverse outcomes following lumbar spinal fusion. No previous study has examined rates of electrolyte disturbances after interbody fusions and compared them between anterior/lateral and posterior-based interbody fusions. The purpose of this study is to identify the incidence of electrolyte disturbances following lumbar interbody fusion and compare the difference in incidence between anterior/lateral lumbar interbody fusions (ALIF/LLIF) and posterior/transforaminal lumbar interbody fusions (PLIF/TLIF).
Methods: A large multi-payer database was queried to identify patients who underwent ALIF/LLIF or PLIF/TLIF from 2010 to 2022.
The incidence of electrolyte abnormalities following each procedure was examined for up to 7 days postoperatively. The cohorts were matched 1 : 1 by demographics and comorbidities.
Results: Among 132,837 ALIF/LLIF and 492,129 PLIF/TLIF patients, the mean age was 60.18 years, 57.5% were female, and the mean Charlson Comorbidity Index was 1.76. There was a downward trend in the incidences of electrolyte abnormalities over the postoperative course except for hypercalcemia (anterior/lateral: p = 0.368; posterior: p = 0.764) and alkalosis (anterior/lateral: p = 0.764; posterior: p = 0.764) in both cohorts, as well as hypernatremia (p = 0.368) in the anterior/lateral cohort, in the first 7 days postoperatively. Patients with electrolyte abnormalities had higher rates of early postoperative ileus (5.84% vs. 1.26%), longer length of stay (9.22 vs. 6.08), higher rates of 90-day readmissions (17.30% vs. 4.48%), and higher costs ($19,946.70 vs. $15,190.87) (all p < 0.001). After matching, the anterior/lateral cohort had higher rates of hypokalemia (anterior = 1.19% vs. posterior = 1.00%, p < 0.001) and acidosis (0.25% vs. 0.18%, p < 0.001) than the posterior cohort.
Conclusions: Electrolyte disturbance following lumbar interbody fusion is associated with ileus, prolonged length of stay, and increased readmission rates and cost. Given the influence of electrolyte disturbances on postoperative outcomes, ongoing efforts to identify the prevalence and risk factors for electrolyte derangement in the perioperative period are warranted. KCI Citation Count: 0 |
| Author | Singh, Manjot Quon, Robert Knebel, Ashley McDonald, Christopher Daniels, Alan H. Diebo, Bassel G Daher, Mohammad Nassar, Joseph E |
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| References | Potter (10.4055/cios25107_ref7) 2005; 18 Brau (10.4055/cios25107_ref17) 2004; 4 10.4055/cios25107_ref18 Ranti (10.4055/cios25107_ref6) 2020; 45 Hackenberg (10.4055/cios25107_ref10) 2005; 14 10.4055/cios25107_ref15 Grandjean (10.4055/cios25107_ref1) 2007; 26 Lee Hamm (10.4055/cios25107_ref20) 2013; 33 10.4055/cios25107_ref21 Wang (10.4055/cios25107_ref5) 2016; 16 Lenz (10.4055/cios25107_ref13) 2022; 16 El-Sharkawy (10.4055/cios25107_ref2) 2014; 33 Kinoshita (10.4055/cios25107_ref19) 2025; 15 Matsen (10.4055/cios25107_ref3) 2015; 97 Niemeyer (10.4055/cios25107_ref9) 2006; 59 Daher (10.4055/cios25107_ref12) 2024; 182 Ploumis (10.4055/cios25107_ref8) 2008; 21 Jiang (10.4055/cios25107_ref11) 2012; 132 Matsukura (10.4055/cios25107_ref14) 2021; 10 Graboyes (10.4055/cios25107_ref4) 2017; 127 Inamasu (10.4055/cios25107_ref16) 2006; 148 |
| References_xml | – ident: 10.4055/cios25107_ref15 – volume: 21 start-page: 120 issue: 2 year: 2008 ident: 10.4055/cios25107_ref8 publication-title: J Spinal Disord Tech doi: 10.1097/BSD.0b013e318060092f – ident: 10.4055/cios25107_ref18 – volume: 15 start-page: 1094 issue: 2 year: 2025 ident: 10.4055/cios25107_ref19 publication-title: Global Spine J doi: 10.1177/21925682231224389 – volume: 16 start-page: 418 issue: 1 year: 2016 ident: 10.4055/cios25107_ref5 publication-title: BMC Psychiatry doi: 10.1186/s12888-016-1130-0 – volume: 59 start-page: 1271 issue: 6 year: 2006 ident: 10.4055/cios25107_ref9 publication-title: Neurosurgery doi: 10.1227/01.NEU.0000245609.01732.E4 – volume: 26 start-page: 549S issue: 5 Suppl year: 2007 ident: 10.4055/cios25107_ref1 publication-title: J Am Coll Nutr doi: 10.1080/07315724.2007.10719657 – volume: 18 start-page: 337 issue: 4 year: 2005 ident: 10.4055/cios25107_ref7 publication-title: J Spinal Disord Tech doi: 10.1097/01.bsd.0000166642.69189.45 – volume: 182 start-page: 91 year: 2024 ident: 10.4055/cios25107_ref12 publication-title: World Neurosurg doi: 10.1016/j.wneu.2023.11.094 – volume: 16 start-page: 141 issue: 1 year: 2022 ident: 10.4055/cios25107_ref13 publication-title: Asian Spine J doi: 10.31616/asj.2020.0405 – volume: 10 start-page: 4737 issue: 20 year: 2021 ident: 10.4055/cios25107_ref14 publication-title: J Clin Med doi: 10.3390/jcm10204737 – volume: 97 start-page: 1255 issue: 15 year: 2015 ident: 10.4055/cios25107_ref3 publication-title: J Bone Joint Surg Am doi: 10.2106/JBJS.N.01107 – volume: 14 start-page: 551 issue: 6 year: 2005 ident: 10.4055/cios25107_ref10 publication-title: Eur Spine J doi: 10.1007/s00586-004-0830-1 – volume: 4 start-page: 409 issue: 4 year: 2004 ident: 10.4055/cios25107_ref17 publication-title: Spine J doi: 10.1016/j.spinee.2003.12.003 – ident: 10.4055/cios25107_ref21 – volume: 127 start-page: 337 issue: 2 year: 2017 ident: 10.4055/cios25107_ref4 publication-title: Laryngo-scope doi: 10.1002/lary.25997 – volume: 132 start-page: 1259 issue: 9 year: 2012 ident: 10.4055/cios25107_ref11 publication-title: Arch Orthop Trauma Surg doi: 10.1007/s00402-012-1546-z – volume: 33 start-page: 6 issue: 1 year: 2014 ident: 10.4055/cios25107_ref2 publication-title: Clin Nutr doi: 10.1016/j.clnu.2013.11.010 – volume: 33 start-page: 257 issue: 3 year: 2013 ident: 10.4055/cios25107_ref20 publication-title: Semin Nephrol doi: 10.1016/j.semnephrol.2013.04.006 – volume: 45 start-page: E704 issue: 12 year: 2020 ident: 10.4055/cios25107_ref6 publication-title: Spine (Phila Pa 1976) doi: 10.1097/BRS.0000000000003412 – volume: 148 start-page: 375 issue: 4 year: 2006 ident: 10.4055/cios25107_ref16 publication-title: Acta Neurochir (Wien) doi: 10.1007/s00701-005-0669-1 |
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| Title | Electrolyte Disturbances after Lumbar Interbody Fusion: A Comparison of Anterior/Lateral and Posterior Approaches |
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