Stable electron-irradiated [1- 13 C]alanine radicals for metabolic imaging with dynamic nuclear polarization

Dissolution dynamic nuclear polarization (dDNP) increases the sensitivity of magnetic resonance experiments by >10 4 -fold, permitting isotopically labeled molecules to be transiently visible in magnetic resonance imaging scans. dDNP mechanistically takes place at ~1 K and requires unpaired elect...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Science advances Jg. 11; H. 47; S. eadz4334
Hauptverfasser:	Rooney, Catriona H. E., Lau, Justin Y. C., Hansen, Esben S. S., Christensen, Nichlas Vous, Dang, Duy A., Petersson, Kristoffer, Tullis, Iain D. C., Vojnovic, Borivoj, Smart, Sean, Myers, William, Richardson, Zoe, Lewis, Jarrod, Kennedy, Brett W. C., Bowen, Alice M., Bertelsen, Lotte Bonde, Laustsen, Christoffer, Tyler, Damian J., Miller, Jack J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 21.11.2025
Schlagworte:	Alanine - chemistry Alanine - metabolism Animals Carbon Isotopes - chemistry Electrons Free Radicals - chemistry Kidney - diagnostic imaging Kidney - metabolism Magnetic Resonance Imaging - methods Rats
ISSN:	2375-2548, 2375-2548
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!