A promoter interaction map for cardiovascular disease genetics

Over 500 genetic loci have been associated with risk of cardiovascular diseases (CVDs), however most loci are located in gene-distal non-coding regions and their target genes are not known. Here, we generated high-resolution promoter capture Hi-C (PCHi-C) maps in human induced pluripotent stem cells...

Full description

Saved in:

Bibliographic Details
Published in:	bioRxiv
Main Authors:	Montefiori, Lindsey E, Sobreira, Debora R, Sakabe, Noboru J, Aneas, Ivy, Joslin, Amelia C, Hansen, Grace T, Bozek, Grazyna, Moskowitz, Ivan P, Mcnally, Elizabeth M, Nobrega, Marcelo A
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 08.06.2018 Cold Spring Harbor Laboratory
Edition:	1.1
Subjects:	Cardiomyocytes Cardiovascular diseases Chromatin Gene expression Gene mapping Genetics Pluripotency Single-nucleotide polymorphism Stem cells
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!