A promoter interaction map for cardiovascular disease genetics

Over 500 genetic loci have been associated with risk of cardiovascular diseases (CVDs), however most loci are located in gene-distal non-coding regions and their target genes are not known. Here, we generated high-resolution promoter capture Hi-C (PCHi-C) maps in human induced pluripotent stem cells...

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Podrobná bibliografia
Vydané v:	bioRxiv
Hlavní autori:	Montefiori, Lindsey E, Sobreira, Debora R, Sakabe, Noboru J, Aneas, Ivy, Joslin, Amelia C, Hansen, Grace T, Bozek, Grazyna, Moskowitz, Ivan P, Mcnally, Elizabeth M, Nobrega, Marcelo A
Médium:	Paper
Jazyk:	English
Vydavateľské údaje:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 08.06.2018 Cold Spring Harbor Laboratory
Vydanie:	1.1
Predmet:	Cardiomyocytes Cardiovascular diseases Chromatin Gene expression Gene mapping Genetics Pluripotency Single-nucleotide polymorphism Stem cells
ISSN:	2692-8205, 2692-8205
On-line prístup:	Získať plný text
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