Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

Schizophrenia (SCZ), bipolar disorder (BD) and recurrent major depressive disorder (rMDD) are common psychiatric illnesses. All have been associated with lower cognitive ability, and show evidence of genetic overlap and substantial evidence of pleiotropy with cognitive function and neuroticism. Disr...

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Bibliographic Details

Published in:	bioRxiv
Main Authors:	Teng, Shaolei, Thomson, Pippa, Mccarthy, Shane, Kramer, Melissa, Muller, Stephanie, Lihm, Jayon, Morris, Stewart, Soares, Dinesh, Hennah, William, Harris, Sarah, Luiz Miguel Camargo, Malkov, Vladislav, Mcintosh, Andrew, Millar, J Kirsty, Blackwood, Douglas, Evans, Kathryn, Deary, Ian, Porteous, David, Mccombie, W Richard
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 27.10.2016 Cold Spring Harbor Laboratory
Edition:	1.1
Subjects:	Bipolar disorder Cognitive ability Disc1 protein Genetics Mental disorders Neurodevelopmental disorders Neurosis Phenotypes Pleiotropy Schizophrenia
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
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