Dimensionality Reduction and Denoising of Spatial Transcriptomics Data Using Dual-Channel Masked Graph Autoencoder

Recent advances in spatial transcriptomics (ST) technology allow researchers to comprehensively measure gene expression patterns at the level of individual cells or even subcellular compartments while preserving the spatial context of their tissue. Spatial domain identification is a critical task in...

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Bibliographic Details
Published in:bioRxiv
Main Authors: Min, Wenwen, Fang, Donghai, Chen, Jinyu, Zhang, Shihua
Format: Paper
Language:English
Published: Cold Spring Harbor Laboratory 02.06.2024
Edition:1.1
Subjects:
ISSN:2692-8205
Online Access:Get full text
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