Regional brain atrophy and functional disconnection across Alzheimer's disease evolution

ObjectiveTo assess the contribution of regional grey matter (GM) atrophy and functional disconnection in determining the level of cognitive decline in patients with Alzheimer's disease (AD) at different clinical stages.MethodsTen patients with amnesic mild cognitive impairment (a-MCI), 11 patie...

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Bibliographic Details
Published in:	Journal of neurology, neurosurgery and psychiatry Vol. 82; no. 1; pp. 58 - 66
Main Authors:	Gili, T, Cercignani, M, Serra, L, Perri, R, Giove, F, Maraviglia, B, Caltagirone, C, Bozzali, M
Format:	Journal Article
Language:	English
Published:	London BMJ Publishing Group Ltd 01.01.2011 BMJ Publishing Group BMJ Publishing Group LTD
Subjects:	Aged Alzheimer Disease - pathology Alzheimer Disease - psychology Alzheimer's disease Amnesia - pathology Amnesia - psychology Atrophy Biological and medical sciences Brain Brain - pathology Cognition Disorders - pathology Cognition Disorders - psychology Cognitive ability Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia Disease Progression Female Fourier transforms Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Medical sciences Memory Middle Aged Nerve Net - pathology Neural Pathways - pathology Neurology Neuropsychological Tests Neuropsychology Atrophy Nervous system diseases Alzheimer disease Central nervous system disease Central nervous system Evolution Degenerative disease Cerebral disorder Encephalon ALZHEIMER'S DISEASE DEMENTIA COGNITION DISCONNECTION IMAGE ANALYSIS
ISSN:	0022-3050, 1468-330X, 1468-330X
Online Access:	Get full text
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