Trans-arterial chemoembolization as a loco-regional inducer of immunogenic cell death in hepatocellular carcinoma: implications for immunotherapy

BackgroundModulation of adaptive immunity may underscore the efficacy of trans-arterial chemoembolization (TACE). We evaluated the influence of TACE on T-cell function by phenotypic lymphocyte characterization in samples of patients undergoing surgery with (T+) or without (T-) prior-TACE treatment.M...

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Bibliographic Details
Published in:	Journal for immunotherapy of cancer Vol. 9; no. 9; p. e003311
Main Authors:	Pinato, David J., Murray, Sam M, Forner, Alejandro, Kaneko, Takahiro, Fessas, Petros, Toniutto, Pierluigi, Mínguez, Beatriz, Cacciato, Valentina, Avellini, Claudio, Diaz, Alba, Boyton, Rosemary J., Altmann, Daniel M., Goldin, Robert D, Akarca, Ayse U, Marafioti, Teresa, Mauri, Francesco A, Casagrande, Edoardo, Grillo, Federica, Giannini, Edoardo, Bhoori, Sherrie, Mazzaferro, Vincenzo
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group Ltd 01.09.2021 BMJ Publishing Group LTD BMJ Publishing Group
Series:	Original research
Subjects:	Adult Aged Apoptosis Cancer Cancer therapies Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - pathology Cell death Chemoembolization Chemoembolization, Therapeutic - methods Chemotherapy Clinical trials Clinical/Translational Cancer Immunotherapy Cytotoxicity Embolization Female Gene expression Humans Immunogenic Cell Death - drug effects Immunotherapy Immunotherapy - methods Ligands Liver cancer liver neoplasms Liver Neoplasms - drug therapy Liver Neoplasms - pathology Male Middle Aged Patients Surgery Tumors United Kingdom > UK New York United States > US liver neoplasms immunotherapy
ISSN:	2051-1426, 2051-1426
Online Access:	Get full text
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