Place and causes of acute cardiovascular mortality during the COVID-19 pandemic

ObjectiveTo describe the place and causes of acute cardiovascular death during the COVID-19 pandemic.MethodsRetrospective cohort of adult (age ≥18 years) acute cardiovascular deaths (n=5 87 225) in England and Wales, from 1 January 2014 to 30 June 2020. The exposure was the COVID-19 pandemic (from o...

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Vydané v:Heart (British Cardiac Society) Ročník 107; číslo 2; s. 113 - 119
Hlavní autori: Wu, Jianhua, Mamas, Mamas A, Mohamed, Mohamed O, Kwok, Chun Shing, Roebuck, Chris, Humberstone, Ben, Denwood, Tom, Luescher, Thomas, de Belder, Mark A, Deanfield, John E, Gale, Chris P
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: England BMJ Publishing Group Ltd and British Cardiovascular Society 01.01.2021
BMJ Publishing Group LTD
BMJ Publishing Group
Edícia:Original research
Predmet:
Acute Coronary Syndrome - etiology
Acute Coronary Syndrome - mortality
Acute coronary syndromes
Adult
Age
Aged
Aged, 80 and over
Algorithms
Cardiac arrhythmia
Causality
Cause of Death
Coronaviruses
COVID-19
COVID-19 - diagnosis
COVID-19 - epidemiology
Endocarditis
England - epidemiology
Female
Health care policy
Healthcare Delivery, Economics and Global Health
Heart attacks
Heart failure
Hospitalization - statistics & numerical data
Hospitals
Humans
Infections
Male
Middle Aged
Mortality
Mortality - trends
Outcome and Process Assessment, Health Care
Pandemics
Pulmonary embolisms
Residence Characteristics - statistics & numerical data
Retrospective Studies
SARS-CoV-2 - isolation & purification
Stroke
Stroke - etiology
Stroke - mortality
Surveillance
Thrombosis
Womens health
England
United Kingdom > UK
Wales
stroke
acute coronary syndromes
ISSN:1355-6037, 1468-201X, 1468-201X
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Shrnutí:ObjectiveTo describe the place and causes of acute cardiovascular death during the COVID-19 pandemic.MethodsRetrospective cohort of adult (age ≥18 years) acute cardiovascular deaths (n=5 87 225) in England and Wales, from 1 January 2014 to 30 June 2020. The exposure was the COVID-19 pandemic (from onset of the first COVID-19 death in England, 2 March 2020). The main outcome was acute cardiovascular events directly contributing to death.ResultsAfter 2 March 2020, there were 28 969 acute cardiovascular deaths of which 5.1% related to COVID-19, and an excess acute cardiovascular mortality of 2085 (+8%). Deaths in the community accounted for nearly half of all deaths during this period. Death at home had the greatest excess acute cardiovascular deaths (2279, +35%), followed by deaths at care homes and hospices (1095, +32%) and in hospital (50, +0%). The most frequent cause of acute cardiovascular death during this period was stroke (10 318, 35.6%), followed by acute coronary syndrome (ACS) (7 098, 24.5%), heart failure (6 770, 23.4%), pulmonary embolism (2 689, 9.3%) and cardiac arrest (1 328, 4.6%). The greatest cause of excess cardiovascular death in care homes and hospices was stroke (715, +39%), compared with ACS (768, +41%) at home and cardiogenic shock (55, +15%) in hospital.Conclusions and relevanceThe COVID-19 pandemic has resulted in an inflation in acute cardiovascular deaths, nearly half of which occurred in the community and most did not relate to COVID-19 infection suggesting there were delays to seeking help or likely the result of undiagnosed COVID-19.
Bibliografia:Original research
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1355-6037
1468-201X
1468-201X
DOI:10.1136/heartjnl-2020-317912