Cognitive–behavioral therapy-based intervention to treat symptoms of anxiety in pregnancy in a prenatal clinic using non-specialist providers in Pakistan: design of a randomised trial

IntroductionPrenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan.Methods and anal...

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Published in:BMJ open Vol. 10; no. 4; p. e037590
Main Authors: Surkan, Pamela J, Hamdani, Syed Usman, Huma, Zill-e, Nazir, Huma, Atif, Najia, Rowther, Armaan A, Chaudhri, Rizwana, Zafar, Shamsa, Mullany, Luke C, Malik, Abid, Rahman, Atif
Format: Journal Article
Language:English
Published: England British Medical Journal Publishing Group 15.04.2020
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Series:Protocol
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ISSN:2044-6055, 2044-6055
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Abstract IntroductionPrenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan.Methods and analysis Happy Mother, Healthy Baby (HMHB) is a phase three, two-arm, single-blind, individual randomised clinical trial conducted in the outpatient department of Holy Family Hospital, a large public tertiary care facility affiliated with Rawalpindi Medical University (RMU). Pregnant women (enrolled at ≤22 weeks of gestation) receive six individual HMHB sessions based on cognitive–behavioral therapy (CBT) and relaxation techniques that are administered by non-specialist providers and tailored to address anxiety symptoms. Two to six booster sessions are given between the fifth consecutive weekly core session and the sixth core session that occurs in the third trimester. Apart from baseline data, data are collected in the third trimester, at birth and at 6-weeks postpartum. Primary outcomes include diagnoses of postpartum common mental disorders. Secondary outcomes include symptoms of anxiety and of depression, and birth outcomes including small-for-gestational age, low birth weight and preterm birth. An economic analysis will determine the cost effectiveness of the intervention.EthicsEthics approval was obtained from the Johns Hopkins Bloomberg School of Health Institutional Review Board (Baltimore, USA), the Human Development Research Foundation Ethics Committee (Islamabad, Pakistan), the RMU Institutional Research Forum (Rawalpindi, Pakistan) and the National Institute of Mental Health-appointed Global Mental Health Data Safety and Monitoring Board.DisseminationResults from this trial will build evidence for the efficacy of a CBT-based intervention for pregnant women delivered by non-specialised providers. Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries.Trial registration number NCT03880032.
AbstractList IntroductionPrenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan.Methods and analysisHappy Mother, Healthy Baby (HMHB) is a phase three, two-arm, single-blind, individual randomised clinical trial conducted in the outpatient department of Holy Family Hospital, a large public tertiary care facility affiliated with Rawalpindi Medical University (RMU). Pregnant women (enrolled at ≤22 weeks of gestation) receive six individual HMHB sessions based on cognitive–behavioral therapy (CBT) and relaxation techniques that are administered by non-specialist providers and tailored to address anxiety symptoms. Two to six booster sessions are given between the fifth consecutive weekly core session and the sixth core session that occurs in the third trimester. Apart from baseline data, data are collected in the third trimester, at birth and at 6-weeks postpartum. Primary outcomes include diagnoses of postpartum common mental disorders. Secondary outcomes include symptoms of anxiety and of depression, and birth outcomes including small-for-gestational age, low birth weight and preterm birth. An economic analysis will determine the cost effectiveness of the intervention.EthicsEthics approval was obtained from the Johns Hopkins Bloomberg School of Health Institutional Review Board (Baltimore, USA), the Human Development Research Foundation Ethics Committee (Islamabad, Pakistan), the RMU Institutional Research Forum (Rawalpindi, Pakistan) and the National Institute of Mental Health-appointed Global Mental Health Data Safety and Monitoring Board.DisseminationResults from this trial will build evidence for the efficacy of a CBT-based intervention for pregnant women delivered by non-specialised providers. Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries.Trial registration numberNCT03880032.
Prenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan. METHODS AND ANALYSIS: Happy Mother, Healthy Baby (HMHB) is a phase three, two-arm, single-blind, individual randomised clinical trial conducted in the outpatient department of Holy Family Hospital, a large public tertiary care facility affiliated with Rawalpindi Medical University (RMU). Pregnant women (enrolled at ≤22 weeks of gestation) receive six individual HMHB sessions based on cognitive-behavioral therapy (CBT) and relaxation techniques that are administered by non-specialist providers and tailored to address anxiety symptoms. Two to six booster sessions are given between the fifth consecutive weekly core session and the sixth core session that occurs in the third trimester. Apart from baseline data, data are collected in the third trimester, at birth and at 6-weeks postpartum. Primary outcomes include diagnoses of postpartum common mental disorders. Secondary outcomes include symptoms of anxiety and of depression, and birth outcomes including small-for-gestational age, low birth weight and preterm birth. An economic analysis will determine the cost effectiveness of the intervention.INTRODUCTIONPrenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan. METHODS AND ANALYSIS: Happy Mother, Healthy Baby (HMHB) is a phase three, two-arm, single-blind, individual randomised clinical trial conducted in the outpatient department of Holy Family Hospital, a large public tertiary care facility affiliated with Rawalpindi Medical University (RMU). Pregnant women (enrolled at ≤22 weeks of gestation) receive six individual HMHB sessions based on cognitive-behavioral therapy (CBT) and relaxation techniques that are administered by non-specialist providers and tailored to address anxiety symptoms. Two to six booster sessions are given between the fifth consecutive weekly core session and the sixth core session that occurs in the third trimester. Apart from baseline data, data are collected in the third trimester, at birth and at 6-weeks postpartum. Primary outcomes include diagnoses of postpartum common mental disorders. Secondary outcomes include symptoms of anxiety and of depression, and birth outcomes including small-for-gestational age, low birth weight and preterm birth. An economic analysis will determine the cost effectiveness of the intervention.Ethics approval was obtained from the Johns Hopkins Bloomberg School of Health Institutional Review Board (Baltimore, USA), the Human Development Research Foundation Ethics Committee (Islamabad, Pakistan), the RMU Institutional Research Forum (Rawalpindi, Pakistan) and the National Institute of Mental Health-appointed Global Mental Health Data Safety and Monitoring Board.ETHICSEthics approval was obtained from the Johns Hopkins Bloomberg School of Health Institutional Review Board (Baltimore, USA), the Human Development Research Foundation Ethics Committee (Islamabad, Pakistan), the RMU Institutional Research Forum (Rawalpindi, Pakistan) and the National Institute of Mental Health-appointed Global Mental Health Data Safety and Monitoring Board.Results from this trial will build evidence for the efficacy of a CBT-based intervention for pregnant women delivered by non-specialised providers. Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries.DISSEMINATIONResults from this trial will build evidence for the efficacy of a CBT-based intervention for pregnant women delivered by non-specialised providers. Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries.NCT03880032.TRIAL REGISTRATION NUMBERNCT03880032.
IntroductionPrenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan.Methods and analysis Happy Mother, Healthy Baby (HMHB) is a phase three, two-arm, single-blind, individual randomised clinical trial conducted in the outpatient department of Holy Family Hospital, a large public tertiary care facility affiliated with Rawalpindi Medical University (RMU). Pregnant women (enrolled at ≤22 weeks of gestation) receive six individual HMHB sessions based on cognitive–behavioral therapy (CBT) and relaxation techniques that are administered by non-specialist providers and tailored to address anxiety symptoms. Two to six booster sessions are given between the fifth consecutive weekly core session and the sixth core session that occurs in the third trimester. Apart from baseline data, data are collected in the third trimester, at birth and at 6-weeks postpartum. Primary outcomes include diagnoses of postpartum common mental disorders. Secondary outcomes include symptoms of anxiety and of depression, and birth outcomes including small-for-gestational age, low birth weight and preterm birth. An economic analysis will determine the cost effectiveness of the intervention.EthicsEthics approval was obtained from the Johns Hopkins Bloomberg School of Health Institutional Review Board (Baltimore, USA), the Human Development Research Foundation Ethics Committee (Islamabad, Pakistan), the RMU Institutional Research Forum (Rawalpindi, Pakistan) and the National Institute of Mental Health-appointed Global Mental Health Data Safety and Monitoring Board.DisseminationResults from this trial will build evidence for the efficacy of a CBT-based intervention for pregnant women delivered by non-specialised providers. Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries.Trial registration number NCT03880032.
Prenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan. METHODS AND ANALYSIS: (HMHB) is a phase three, two-arm, single-blind, individual randomised clinical trial conducted in the outpatient department of Holy Family Hospital, a large public tertiary care facility affiliated with Rawalpindi Medical University (RMU). Pregnant women (enrolled at ≤22 weeks of gestation) receive six individual HMHB sessions based on cognitive-behavioral therapy (CBT) and relaxation techniques that are administered by non-specialist providers and tailored to address anxiety symptoms. Two to six booster sessions are given between the fifth consecutive weekly core session and the sixth core session that occurs in the third trimester. Apart from baseline data, data are collected in the third trimester, at birth and at 6-weeks postpartum. Primary outcomes include diagnoses of postpartum common mental disorders. Secondary outcomes include symptoms of anxiety and of depression, and birth outcomes including small-for-gestational age, low birth weight and preterm birth. An economic analysis will determine the cost effectiveness of the intervention. Ethics approval was obtained from the Johns Hopkins Bloomberg School of Health Institutional Review Board (Baltimore, USA), the Human Development Research Foundation Ethics Committee (Islamabad, Pakistan), the RMU Institutional Research Forum (Rawalpindi, Pakistan) and the National Institute of Mental Health-appointed Global Mental Health Data Safety and Monitoring Board. Results from this trial will build evidence for the efficacy of a CBT-based intervention for pregnant women delivered by non-specialised providers. Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries. NCT03880032.
Introduction Prenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention initiated in early pregnancy to mid pregnancy among women with clinical or subclinical symptoms of anxiety in Pakistan.Methods and analysis Happy Mother, Healthy Baby (HMHB) is a phase three, two-arm, single-blind, individual randomised clinical trial conducted in the outpatient department of Holy Family Hospital, a large public tertiary care facility affiliated with Rawalpindi Medical University (RMU). Pregnant women (enrolled at ≤22 weeks of gestation) receive six individual HMHB sessions based on cognitive–behavioral therapy (CBT) and relaxation techniques that are administered by non-specialist providers and tailored to address anxiety symptoms. Two to six booster sessions are given between the fifth consecutive weekly core session and the sixth core session that occurs in the third trimester. Apart from baseline data, data are collected in the third trimester, at birth and at 6-weeks postpartum. Primary outcomes include diagnoses of postpartum common mental disorders. Secondary outcomes include symptoms of anxiety and of depression, and birth outcomes including small-for-gestational age, low birth weight and preterm birth. An economic analysis will determine the cost effectiveness of the intervention.Ethics Ethics approval was obtained from the Johns Hopkins Bloomberg School of Health Institutional Review Board (Baltimore, USA), the Human Development Research Foundation Ethics Committee (Islamabad, Pakistan), the RMU Institutional Research Forum (Rawalpindi, Pakistan) and the National Institute of Mental Health-appointed Global Mental Health Data Safety and Monitoring Board.Dissemination Results from this trial will build evidence for the efficacy of a CBT-based intervention for pregnant women delivered by non-specialised providers. Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries.Trial registration number NCT03880032.
Author Rowther, Armaan A
Zafar, Shamsa
Atif, Najia
Chaudhri, Rizwana
Malik, Abid
Huma, Zill-e
Hamdani, Syed Usman
Rahman, Atif
Surkan, Pamela J
Nazir, Huma
Mullany, Luke C
AuthorAffiliation 1 Department of International Health , Johns Hopkins University Bloomberg School of Public Health , Baltimore , Maryland , USA
4 Department of Gynaecology and Obstetrics , Holy Family Hospital, Rawalpindi Medical University , Rawalpindi , Pakistan
5 Department of Obstetrics and Gynaecology , Air University , Islamabad , Pakistan
6 Department of Psychological Sciences , University of Liverpool , Liverpool , UK
2 Human Development Research Foundation , Rawalpindi , Pakistan
3 Institute of Psychiatry , Rawalpindi Medical University , Rawalpindi , Pakistan
AuthorAffiliation_xml – name: 3 Institute of Psychiatry , Rawalpindi Medical University , Rawalpindi , Pakistan
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/32300002$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1097/DBP.0000000000000003
10.1097/PSY.0b013e31820a62ce
10.1016/S0140-6736(10)61508-5
10.1016/j.infbeh.2009.10.005
10.1089/jwh.2014.5150
10.1017/S0033291714000300
10.1100/2012/653098
10.1111/j.1750-8606.2008.00077.x
10.1192/bjp.184.46.s45
10.1016/j.brat.2015.03.009
10.1016/S0140-6736(08)61400-2
10.1186/1741-7015-8-38
10.1007/s00737-015-0498-z
10.1093/jn/138.4.799
10.1001/jama.291.21.2581
10.1016/j.eurpsy.2004.09.025
10.1111/mcn.12170
10.26719/2013.19.4.327
10.1016/j.jad.2010.08.002
10.2217/WHE.11.96
10.1007/s00737-007-0193-9
10.1542/peds.2005-1551
10.1111/j.1469-7610.2006.01714.x
10.1016/S0079-6123(07)67002-2
10.1097/00004583-200212000-00019
10.2471/BLT.12.109819
10.1016/j.genhosppsych.2004.02.006
10.1016/j.jad.2014.12.041
10.1016/j.bpobgyn.2016.05.007
10.2471/BLT.11.091850
10.1007/s00737-006-0129-9
10.1177/0020764008094645
10.1016/s0272-7358(98)00100-7
10.1016/S2214-109X(13)70006-8
10.1016/S0140-6736(07)61239-2
10.3389/fpsyt.2019.00927
10.1001/archgenpsychiatry.2010.111
10.1017/S0033291703008286
10.1371/journal.pone.0116510
10.1016/S0272-7358(98)00100-7
10.1100/2012/840421
10.2217/whe.11.96
10.1007/978-1-4899-3242-6
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Issue 4
Keywords therapeutics
anxiety disorders
depression & mood disorders
prenatal diagnosis
Language English
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References Seckl (R20) 2008; 167
Zelkowitz, Papageorgiou (R23) 2012; 8
Rahman, Iqbal, Harrington (R38) 2003; 33
Cape, Whittington, Buszewicz (R30) 2010; 8
Lee, Katz, Blencowe (R29) 2013; 1
Rahman, Malik, Sikander (R36) 2008; 372
Wachs, Black, Engle (R2) 2009; 3
McLearn, Minkovitz, Strobino (R11) 2006; 118
Surkan, Patel, Rahman (R18) 2016; 36
Tarabulsy, Pearson, Vaillancourt-Morel (R21) 2014; 35
Humayun, Haider, Imran (R40) 2013; 19
Green, Haber, Frey (R31) 2015; 18
Coelho, Murray, Royal-Lawson (R5) 2011; 129
Husain, Bevc, Husain (R9) 2006; 9
Kohrt, Jordans, Rai (R43) 2015; 69
Grote, Bridge, Gavin (R15) 2010; 67
Niaz, Izhar, Bhatti (R3) 2004; 20
Lovejoy, Graczyk, O'Hare (R14) 2000; 20
Patel, Weiss, Chowdhary (R45) 2010; 376
Waqas, Raza, Lodhi (R4) 2015; 10
Talge, Neal, Glover (R19) 2007; 48
Chisholm, Conroy, Glangeaud-Freudenthal (R34) 2004; 46
Rahman, Fisher, Bower (R46) 2013; 91
Ali, Azam, Ali (R39) 2012; 2012
Demyttenaere, Bruffaerts, Posada-Villa (R25) 2004; 291
Robertson, Grace, Wallington (R7) 2004; 26
Khashan, Everard, McCowan (R27) 2014; 44
Misri, Abizadeh, Sanders (R32) 2015; 24
Fisher, Cabral de Mello, Patel (R1) 2012; 90
Karmaliani, Asad, Bann (R44) 2009; 55
Field (R10) 2010; 33
Rahman (R35) 2007; 10
Atif, Nazir, Zafar (R37); 10:927
Pollack (R26) 2005; 66
Norhayati, Hazlina, Asrenee (R6) 2015; 175
O'Connor, Heron, Glover (R22) 2002; 41
Hurley, Black, Papas (R13) 2008; 138
Rahman, Hafeez, Bilal (R12) 2016; 12
Sutter-Dallay, Giaconne-Marcesche, Glatigny-Dallay (R8) 2004; 19
Class, Lichtenstein, Långström (R28) 2011; 73
Saxena, Thornicroft, Knapp (R24) 2007; 370
Talge, Neal, Glover 2007; 48
Ali, Azam, Ali 2012; 2012
Atif, Nazir, Zafar; 10:927
Rahman, Iqbal, Harrington 2003; 33
Karmaliani, Asad, Bann 2009; 55
Rahman, Malik, Sikander 2008; 372
Sutter-Dallay, Giaconne-Marcesche, Glatigny-Dallay 2004; 19
Lovejoy, Graczyk, O'Hare 2000; 20
Rahman 2007; 10
Rahman, Hafeez, Bilal 2016; 12
Tarabulsy, Pearson, Vaillancourt-Morel 2014; 35
Rahman, Fisher, Bower 2013; 91
Surkan, Patel, Rahman 2016; 36
McLearn, Minkovitz, Strobino 2006; 118
Patel, Weiss, Chowdhary 2010; 376
Hurley, Black, Papas 2008; 138
Fisher, Cabral de Mello, Patel 2012; 90
Kohrt, Jordans, Rai 2015; 69
Husain, Bevc, Husain 2006; 9
Coelho, Murray, Royal-Lawson 2011; 129
Grote, Bridge, Gavin 2010; 67
Niaz, Izhar, Bhatti 2004; 20
Seckl 2008; 167
Chisholm, Conroy, Glangeaud-Freudenthal 2004; 46
Humayun, Haider, Imran 2013; 19
O'Connor, Heron, Glover 2002; 41
Zelkowitz, Papageorgiou 2012; 8
Class, Lichtenstein, Långström 2011; 73
Demyttenaere, Bruffaerts, Posada-Villa 2004; 291
Saxena, Thornicroft, Knapp 2007; 370
Misri, Abizadeh, Sanders 2015; 24
Wachs, Black, Engle 2009; 3
Khashan, Everard, McCowan 2014; 44
Norhayati, Hazlina, Asrenee 2015; 175
Pollack 2005; 66
Cape, Whittington, Buszewicz 2010; 8
Robertson, Grace, Wallington 2004; 26
Field 2010; 33
Lee, Katz, Blencowe 2013; 1
Green, Haber, Frey 2015; 18
Waqas, Raza, Lodhi 2015; 10
2025101811301502000_10.4.e037590.30
Khashan (2025101811301502000_10.4.e037590.27) 2014; 44
Chisholm (2025101811301502000_10.4.e037590.34) 2004; 46
Pollack (2025101811301502000_10.4.e037590.26) 2005; 66
Lee (2025101811301502000_10.4.e037590.29) 2013; 1
2025101811301502000_10.4.e037590.9
2025101811301502000_10.4.e037590.2
2025101811301502000_10.4.e037590.48
2025101811301502000_10.4.e037590.1
2025101811301502000_10.4.e037590.25
2025101811301502000_10.4.e037590.47
2025101811301502000_10.4.e037590.28
Humayun (2025101811301502000_10.4.e037590.40) 2013; 19
Waqas (2025101811301502000_10.4.e037590.4) 2015; 10
Surkan (2025101811301502000_10.4.e037590.18) 2016; 36
2025101811301502000_10.4.e037590.6
2025101811301502000_10.4.e037590.22
2025101811301502000_10.4.e037590.44
2025101811301502000_10.4.e037590.5
2025101811301502000_10.4.e037590.43
2025101811301502000_10.4.e037590.8
2025101811301502000_10.4.e037590.24
2025101811301502000_10.4.e037590.46
2025101811301502000_10.4.e037590.7
2025101811301502000_10.4.e037590.23
2025101811301502000_10.4.e037590.45
2025101811301502000_10.4.e037590.20
2025101811301502000_10.4.e037590.42
2025101811301502000_10.4.e037590.41
Niaz (2025101811301502000_10.4.e037590.3) 2004; 20
2025101811301502000_10.4.e037590.19
Hurley (2025101811301502000_10.4.e037590.13) 2008; 138
Green (2025101811301502000_10.4.e037590.31) 2015; 18
2025101811301502000_10.4.e037590.15
2025101811301502000_10.4.e037590.37
2025101811301502000_10.4.e037590.14
2025101811301502000_10.4.e037590.36
2025101811301502000_10.4.e037590.17
2025101811301502000_10.4.e037590.39
Rahman (2025101811301502000_10.4.e037590.12) 2016; 12
2025101811301502000_10.4.e037590.16
2025101811301502000_10.4.e037590.38
2025101811301502000_10.4.e037590.11
2025101811301502000_10.4.e037590.33
2025101811301502000_10.4.e037590.10
2025101811301502000_10.4.e037590.32
Tarabulsy (2025101811301502000_10.4.e037590.21) 2014; 35
2025101811301502000_10.4.e037590.35
References_xml – volume: 35
  start-page: 38
  year: 2014
  ident: R21
  article-title: Meta-Analytic findings of the relation between maternal prenatal stress and anxiety and child cognitive outcome
  publication-title: J Dev Behav Pediatr
  doi: 10.1097/DBP.0000000000000003
– volume: 73
  start-page: 234
  year: 2011
  ident: R28
  article-title: Timing of prenatal maternal exposure to severe life events and adverse pregnancy outcomes: a population study of 2.6 million pregnancies
  publication-title: Psychosom Med
  doi: 10.1097/PSY.0b013e31820a62ce
– volume: 376
  start-page: 2086
  year: 2010
  ident: R45
  article-title: Effectiveness of an intervention led by lay health counsellors for depressive and anxiety disorders in primary care in Goa, India (MANAS): a cluster randomised controlled trial
  publication-title: Lancet
  doi: 10.1016/S0140-6736(10)61508-5
– volume: 33
  start-page: 1
  year: 2010
  ident: R10
  article-title: Postpartum depression effects on early interactions, parenting, and safety practices: a review
  publication-title: Infant Behav Dev
  doi: 10.1016/j.infbeh.2009.10.005
– volume: 24
  start-page: 762
  year: 2015
  ident: R32
  article-title: Perinatal generalized anxiety disorder: assessment and treatment
  publication-title: J Womens Health
  doi: 10.1089/jwh.2014.5150
– volume: 44
  start-page: 2799
  year: 2014
  ident: R27
  article-title: Second-Trimester maternal distress increases the risk of small for gestational age
  publication-title: Psychol Med
  doi: 10.1017/S0033291714000300
– volume: 2012
  start-page: 1
  year: 2012
  ident: R39
  article-title: Frequency and associated factors for anxiety and depression in pregnant women: a hospital-based cross-sectional study
  publication-title: ScientificWorldJournal
  doi: 10.1100/2012/653098
– volume: 3
  start-page: 51
  year: 2009
  ident: R2
  article-title: Maternal depression: a global threat to children’s health, development, and behavior and to human rights
  publication-title: Child Dev Perspect
  doi: 10.1111/j.1750-8606.2008.00077.x
– volume: 46
  start-page: s45
  year: 2004
  ident: R34
  article-title: Health services research into postnatal depression: results from a preliminary cross-cultural study
  publication-title: Br J Psychiatry Suppl
  doi: 10.1192/bjp.184.46.s45
– volume: 69
  start-page: 11
  year: 2015
  ident: R43
  article-title: Therapist competence in global mental health: development of the enhancing assessment of common therapeutic factors (ENACT) rating scale
  publication-title: Behav Res Ther
  doi: 10.1016/j.brat.2015.03.009
– volume: 372
  start-page: 902
  year: 2008
  ident: R36
  article-title: Cognitive behaviour therapy-based intervention by community health workers for mothers with depression and their infants in rural Pakistan: a cluster-randomised controlled trial
  publication-title: Lancet
  doi: 10.1016/S0140-6736(08)61400-2
– volume: 20
  start-page: 117
  year: 2004
  ident: R3
  article-title: Anxiety and depression in pregnant women presenting in the OPD of a teaching hospital
  publication-title: Pak J Med Sci
– volume: 8
  year: 2010
  ident: R30
  article-title: Brief psychological therapies for anxiety and depression in primary care: meta-analysis and meta-regression
  publication-title: BMC Med
  doi: 10.1186/1741-7015-8-38
– volume: 18
  start-page: 631
  year: 2015
  ident: R31
  article-title: Cognitive-Behavioral group treatment for perinatal anxiety: a pilot study
  publication-title: Arch Womens Ment Health
  doi: 10.1007/s00737-015-0498-z
– volume: 138
  start-page: 799
  year: 2008
  ident: R13
  article-title: Maternal symptoms of stress, depression, and anxiety are related to nonresponsive feeding styles in a statewide sample of WIC participants
  publication-title: J Nutr
  doi: 10.1093/jn/138.4.799
– volume: 291
  start-page: 2581
  year: 2004
  ident: R25
  article-title: Prevalence, severity, and unmet need for treatment of mental disorders in the world Health organization world mental health surveys
  publication-title: JAMA
  doi: 10.1001/jama.291.21.2581
– volume: 19
  start-page: 459
  year: 2004
  ident: R8
  article-title: Women with anxiety disorders during pregnancy are at increased risk of intense postnatal depressive symptoms: a prospective survey of the MATQUID cohort
  publication-title: Eur Psychiatry
  doi: 10.1016/j.eurpsy.2004.09.025
– volume: 12
  start-page: 452
  year: 2016
  ident: R12
  article-title: The impact of perinatal depression on exclusive breastfeeding: a cohort study
  publication-title: Matern Child Nutr
  doi: 10.1111/mcn.12170
– volume: 19
  start-page: 327
  year: 2013
  ident: R40
  article-title: Antenatal depression and its predictors in Lahore, Pakistan
  publication-title: East Mediterr Health J
  doi: 10.26719/2013.19.4.327
– volume: 129
  start-page: 348
  year: 2011
  ident: R5
  article-title: Antenatal anxiety disorder as a predictor of postnatal depression: a longitudinal study
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2010.08.002
– volume: 8
  start-page: 205
  year: 2012
  ident: R23
  article-title: Easing maternal anxiety: an update
  publication-title: Womens Health
  doi: 10.2217/WHE.11.96
– volume: 66
  start-page: 22
  year: 2005
  ident: R26
  article-title: Comorbid anxiety and depression
  publication-title: J Clin Psychiatry
– volume: 10
  start-page: 211
  year: 2007
  ident: R35
  article-title: Challenges and opportunities in developing a psychological intervention for perinatal depression in rural Pakistan--a multi-method study
  publication-title: Arch Womens Ment Health
  doi: 10.1007/s00737-007-0193-9
– volume: 118
  start-page: e174
  year: 2006
  ident: R11
  article-title: The timing of maternal depressive symptoms and mothers' parenting practices with young children: implications for pediatric practice
  publication-title: Pediatrics
  doi: 10.1542/peds.2005-1551
– volume: 48
  start-page: 245
  year: 2007
  ident: R19
  article-title: Antenatal maternal stress and long-term effects on child neurodevelopment: how and why?
  publication-title: J Child Psychol Psychiatry
  doi: 10.1111/j.1469-7610.2006.01714.x
– volume: 167
  start-page: 17
  year: 2008
  ident: R20
  article-title: Glucocorticoids, developmental 'programming' and the risk of affective dysfunction
  publication-title: Prog Brain Res
  doi: 10.1016/S0079-6123(07)67002-2
– volume: 41
  start-page: 1470
  year: 2002
  ident: R22
  article-title: Antenatal anxiety predicts child behavioral/emotional problems independently of postnatal depression
  publication-title: J Am Acad Child Adolesc Psychiatry
  doi: 10.1097/00004583-200212000-00019
– volume: 91
  start-page: 593
  year: 2013
  ident: R46
  article-title: Interventions for common perinatal mental disorders in women in low- and middle-income countries: a systematic review and meta-analysis
  publication-title: Bull World Health Organ
  doi: 10.2471/BLT.12.109819
– volume: 26
  start-page: 289
  year: 2004
  ident: R7
  article-title: Antenatal risk factors for postpartum depression: a synthesis of recent literature
  publication-title: Gen Hosp Psychiatry
  doi: 10.1016/j.genhosppsych.2004.02.006
– volume: 175
  start-page: 34
  year: 2015
  ident: R6
  article-title: Magnitude and risk factors for postpartum symptoms: a literature review
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2014.12.041
– volume: 36
  start-page: 156
  year: 2016
  ident: R18
  article-title: Preventing infant and child morbidity and mortality due to maternal depression
  publication-title: Best Pract Res Clin Obstet Gynaecol
  doi: 10.1016/j.bpobgyn.2016.05.007
– volume: 90
  start-page: 139
  year: 2012
  ident: R1
  article-title: Prevalence and determinants of common perinatal mental disorders in women in low- and lower-middle-income countries: a systematic review
  publication-title: Bull World Health Organ
  doi: 10.2471/BLT.11.091850
– volume: 9
  start-page: 197
  year: 2006
  ident: R9
  article-title: Prevalence and social correlates of postnatal depression in a low income country
  publication-title: Arch Womens Ment Health
  doi: 10.1007/s00737-006-0129-9
– volume: 55
  start-page: 414
  year: 2009
  ident: R44
  article-title: Prevalence of anxiety, depression and associated factors among pregnant women of Hyderabad, Pakistan
  publication-title: Int J Soc Psychiatry
  doi: 10.1177/0020764008094645
– volume: 20
  start-page: 561
  year: 2000
  ident: R14
  article-title: Maternal depression and parenting behavior: a meta-analytic review
  publication-title: Clin Psychol Rev
  doi: 10.1016/s0272-7358(98)00100-7
– volume: 1
  start-page: e26
  year: 2013
  ident: R29
  article-title: National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010
  publication-title: Lancet Glob Health
  doi: 10.1016/S2214-109X(13)70006-8
– volume: 370
  start-page: 878
  year: 2007
  ident: R24
  article-title: Resources for mental health: scarcity, inequity, and inefficiency
  publication-title: Lancet
  doi: 10.1016/S0140-6736(07)61239-2
– volume: 10:927
  ident: R37
  article-title: Development of a psychological intervention to address anxiety during pregnancy in a low-income country
  publication-title: Front. Psychiatry
  doi: 10.3389/fpsyt.2019.00927
– volume: 67
  start-page: 1012
  year: 2010
  ident: R15
  article-title: A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2010.111
– volume: 33
  start-page: 1161
  year: 2003
  ident: R38
  article-title: Life events, social support and depression in childbirth: perspectives from a rural community in the developing world
  publication-title: Psychol Med
  doi: 10.1017/S0033291703008286
– volume: 10
  year: 2015
  ident: R4
  article-title: Psychosocial factors of antenatal anxiety and depression in Pakistan: is social support a mediator?
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0116510
– volume: 48
  start-page: 245
  year: 2007
  article-title: Antenatal maternal stress and long-term effects on child neurodevelopment: how and why?
  publication-title: J Child Psychol Psychiatry
  doi: 10.1111/j.1469-7610.2006.01714.x
– volume: 10
  start-page: 211
  year: 2007
  article-title: Challenges and opportunities in developing a psychological intervention for perinatal depression in rural Pakistan--a multi-method study
  publication-title: Arch Womens Ment Health
  doi: 10.1007/s00737-007-0193-9
– volume: 2012
  start-page: 1
  year: 2012
  article-title: Frequency and associated factors for anxiety and depression in pregnant women: a hospital-based cross-sectional study
  publication-title: ScientificWorldJournal
  doi: 10.1100/2012/653098
– volume: 376
  start-page: 2086
  year: 2010
  article-title: Effectiveness of an intervention led by lay health counsellors for depressive and anxiety disorders in primary care in Goa, India (MANAS): a cluster randomised controlled trial
  publication-title: Lancet
  doi: 10.1016/S0140-6736(10)61508-5
– volume: 3
  start-page: 51
  year: 2009
  article-title: Maternal depression: a global threat to children’s health, development, and behavior and to human rights
  publication-title: Child Dev Perspect
  doi: 10.1111/j.1750-8606.2008.00077.x
– volume: 370
  start-page: 878
  year: 2007
  article-title: Resources for mental health: scarcity, inequity, and inefficiency
  publication-title: Lancet
  doi: 10.1016/S0140-6736(07)61239-2
– volume: 8
  start-page: 205
  year: 2012
  article-title: Easing maternal anxiety: an update
  publication-title: Womens Health
  doi: 10.2217/WHE.11.96
– volume: 90
  start-page: 139
  year: 2012
  article-title: Prevalence and determinants of common perinatal mental disorders in women in low- and lower-middle-income countries: a systematic review
  publication-title: Bull World Health Organ
  doi: 10.2471/BLT.11.091850
– volume: 20
  start-page: 117
  year: 2004
  article-title: Anxiety and depression in pregnant women presenting in the OPD of a teaching hospital
  publication-title: Pak J Med Sci
– volume: 73
  start-page: 234
  year: 2011
  article-title: Timing of prenatal maternal exposure to severe life events and adverse pregnancy outcomes: a population study of 2.6 million pregnancies
  publication-title: Psychosom Med
  doi: 10.1097/PSY.0b013e31820a62ce
– volume: 118
  start-page: e174
  year: 2006
  article-title: The timing of maternal depressive symptoms and mothers' parenting practices with young children: implications for pediatric practice
  publication-title: Pediatrics
  doi: 10.1542/peds.2005-1551
– volume: 36
  start-page: 156
  year: 2016
  article-title: Preventing infant and child morbidity and mortality due to maternal depression
  publication-title: Best Pract Res Clin Obstet Gynaecol
  doi: 10.1016/j.bpobgyn.2016.05.007
– volume: 41
  start-page: 1470
  year: 2002
  article-title: Antenatal anxiety predicts child behavioral/emotional problems independently of postnatal depression
  publication-title: J Am Acad Child Adolesc Psychiatry
  doi: 10.1097/00004583-200212000-00019
– volume: 10
  year: 2015
  article-title: Psychosocial factors of antenatal anxiety and depression in Pakistan: is social support a mediator?
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0116510
– volume: 167
  start-page: 17
  year: 2008
  article-title: Glucocorticoids, developmental 'programming' and the risk of affective dysfunction
  publication-title: Prog Brain Res
  doi: 10.1016/S0079-6123(07)67002-2
– volume: 69
  start-page: 11
  year: 2015
  article-title: Therapist competence in global mental health: development of the enhancing assessment of common therapeutic factors (ENACT) rating scale
  publication-title: Behav Res Ther
  doi: 10.1016/j.brat.2015.03.009
– volume: 19
  start-page: 459
  year: 2004
  article-title: Women with anxiety disorders during pregnancy are at increased risk of intense postnatal depressive symptoms: a prospective survey of the MATQUID cohort
  publication-title: Eur Psychiatry
  doi: 10.1016/j.eurpsy.2004.09.025
– volume: 18
  start-page: 631
  year: 2015
  article-title: Cognitive-Behavioral group treatment for perinatal anxiety: a pilot study
  publication-title: Arch Womens Ment Health
  doi: 10.1007/s00737-015-0498-z
– volume: 46
  start-page: s45
  year: 2004
  article-title: Health services research into postnatal depression: results from a preliminary cross-cultural study
  publication-title: Br J Psychiatry Suppl
  doi: 10.1192/bjp.184.46.s45
– volume: 175
  start-page: 34
  year: 2015
  article-title: Magnitude and risk factors for postpartum symptoms: a literature review
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2014.12.041
– volume: 12
  start-page: 452
  year: 2016
  article-title: The impact of perinatal depression on exclusive breastfeeding: a cohort study
  publication-title: Matern Child Nutr
  doi: 10.1111/mcn.12170
– volume: 33
  start-page: 1161
  year: 2003
  article-title: Life events, social support and depression in childbirth: perspectives from a rural community in the developing world
  publication-title: Psychol Med
  doi: 10.1017/S0033291703008286
– volume: 19
  start-page: 327
  year: 2013
  article-title: Antenatal depression and its predictors in Lahore, Pakistan
  publication-title: East Mediterr Health J
  doi: 10.26719/2013.19.4.327
– volume: 55
  start-page: 414
  year: 2009
  article-title: Prevalence of anxiety, depression and associated factors among pregnant women of Hyderabad, Pakistan
  publication-title: Int J Soc Psychiatry
  doi: 10.1177/0020764008094645
– volume: 35
  start-page: 38
  year: 2014
  article-title: Meta-Analytic findings of the relation between maternal prenatal stress and anxiety and child cognitive outcome
  publication-title: J Dev Behav Pediatr
  doi: 10.1097/DBP.0000000000000003
– volume: 33
  start-page: 1
  year: 2010
  article-title: Postpartum depression effects on early interactions, parenting, and safety practices: a review
  publication-title: Infant Behav Dev
  doi: 10.1016/j.infbeh.2009.10.005
– volume: 67
  start-page: 1012
  year: 2010
  article-title: A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction
  publication-title: Arch Gen Psychiatry
  doi: 10.1001/archgenpsychiatry.2010.111
– volume: 291
  start-page: 2581
  year: 2004
  article-title: Prevalence, severity, and unmet need for treatment of mental disorders in the world Health organization world mental health surveys
  publication-title: JAMA
  doi: 10.1001/jama.291.21.2581
– volume: 1
  start-page: e26
  year: 2013
  article-title: National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010
  publication-title: Lancet Glob Health
  doi: 10.1016/S2214-109X(13)70006-8
– volume: 24
  start-page: 762
  year: 2015
  article-title: Perinatal generalized anxiety disorder: assessment and treatment
  publication-title: J Womens Health
  doi: 10.1089/jwh.2014.5150
– volume: 138
  start-page: 799
  year: 2008
  article-title: Maternal symptoms of stress, depression, and anxiety are related to nonresponsive feeding styles in a statewide sample of WIC participants
  publication-title: J Nutr
  doi: 10.1093/jn/138.4.799
– volume: 20
  start-page: 561
  year: 2000
  article-title: Maternal depression and parenting behavior: a meta-analytic review
  publication-title: Clin Psychol Rev
  doi: 10.1016/s0272-7358(98)00100-7
– volume: 91
  start-page: 593
  year: 2013
  article-title: Interventions for common perinatal mental disorders in women in low- and middle-income countries: a systematic review and meta-analysis
  publication-title: Bull World Health Organ
  doi: 10.2471/BLT.12.109819
– volume: 26
  start-page: 289
  year: 2004
  article-title: Antenatal risk factors for postpartum depression: a synthesis of recent literature
  publication-title: Gen Hosp Psychiatry
  doi: 10.1016/j.genhosppsych.2004.02.006
– volume: 129
  start-page: 348
  year: 2011
  article-title: Antenatal anxiety disorder as a predictor of postnatal depression: a longitudinal study
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2010.08.002
– volume: 8
  year: 2010
  article-title: Brief psychological therapies for anxiety and depression in primary care: meta-analysis and meta-regression
  publication-title: BMC Med
  doi: 10.1186/1741-7015-8-38
– volume: 372
  start-page: 902
  year: 2008
  article-title: Cognitive behaviour therapy-based intervention by community health workers for mothers with depression and their infants in rural Pakistan: a cluster-randomised controlled trial
  publication-title: Lancet
  doi: 10.1016/S0140-6736(08)61400-2
– volume: 44
  start-page: 2799
  year: 2014
  article-title: Second-Trimester maternal distress increases the risk of small for gestational age
  publication-title: Psychol Med
  doi: 10.1017/S0033291714000300
– volume: 10:927
  article-title: Development of a psychological intervention to address anxiety during pregnancy in a low-income country
  publication-title: Front. Psychiatry
  doi: 10.3389/fpsyt.2019.00927
– volume: 66
  start-page: 22
  year: 2005
  article-title: Comorbid anxiety and depression
  publication-title: J Clin Psychiatry
– volume: 9
  start-page: 197
  year: 2006
  article-title: Prevalence and social correlates of postnatal depression in a low income country
  publication-title: Arch Womens Ment Health
  doi: 10.1007/s00737-006-0129-9
– ident: 2025101811301502000_10.4.e037590.46
  doi: 10.2471/BLT.12.109819
– volume: 18
  start-page: 631
  year: 2015
  ident: 2025101811301502000_10.4.e037590.31
  article-title: Cognitive-Behavioral group treatment for perinatal anxiety: a pilot study
  publication-title: Arch Womens Ment Health
  doi: 10.1007/s00737-015-0498-z
– ident: 2025101811301502000_10.4.e037590.14
  doi: 10.1016/S0272-7358(98)00100-7
– ident: 2025101811301502000_10.4.e037590.32
  doi: 10.1089/jwh.2014.5150
– ident: 2025101811301502000_10.4.e037590.17
– ident: 2025101811301502000_10.4.e037590.1
  doi: 10.2471/BLT.11.091850
– ident: 2025101811301502000_10.4.e037590.6
  doi: 10.1016/j.jad.2014.12.041
– ident: 2025101811301502000_10.4.e037590.33
– ident: 2025101811301502000_10.4.e037590.24
  doi: 10.1016/S0140-6736(07)61239-2
– ident: 2025101811301502000_10.4.e037590.36
  doi: 10.1016/S0140-6736(08)61400-2
– volume: 20
  start-page: 117
  year: 2004
  ident: 2025101811301502000_10.4.e037590.3
  article-title: Anxiety and depression in pregnant women presenting in the OPD of a teaching hospital
  publication-title: Pak J Med Sci
– ident: 2025101811301502000_10.4.e037590.5
  doi: 10.1016/j.jad.2010.08.002
– ident: 2025101811301502000_10.4.e037590.10
  doi: 10.1016/j.infbeh.2009.10.005
– volume: 138
  start-page: 799
  year: 2008
  ident: 2025101811301502000_10.4.e037590.13
  article-title: Maternal symptoms of stress, depression, and anxiety are related to nonresponsive feeding styles in a statewide sample of WIC participants
  publication-title: J Nutr
  doi: 10.1093/jn/138.4.799
– ident: 2025101811301502000_10.4.e037590.8
  doi: 10.1016/j.eurpsy.2004.09.025
– ident: 2025101811301502000_10.4.e037590.22
  doi: 10.1097/00004583-200212000-00019
– ident: 2025101811301502000_10.4.e037590.25
  doi: 10.1001/jama.291.21.2581
– volume: 10
  year: 2015
  ident: 2025101811301502000_10.4.e037590.4
  article-title: Psychosocial factors of antenatal anxiety and depression in Pakistan: is social support a mediator?
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0116510
– ident: 2025101811301502000_10.4.e037590.42
– ident: 2025101811301502000_10.4.e037590.43
  doi: 10.1016/j.brat.2015.03.009
– ident: 2025101811301502000_10.4.e037590.11
  doi: 10.1542/peds.2005-1551
– ident: 2025101811301502000_10.4.e037590.20
  doi: 10.1016/S0079-6123(07)67002-2
– ident: 2025101811301502000_10.4.e037590.9
  doi: 10.1007/s00737-006-0129-9
– volume: 12
  start-page: 452
  year: 2016
  ident: 2025101811301502000_10.4.e037590.12
  article-title: The impact of perinatal depression on exclusive breastfeeding: a cohort study
  publication-title: Matern Child Nutr
  doi: 10.1111/mcn.12170
– ident: 2025101811301502000_10.4.e037590.48
– ident: 2025101811301502000_10.4.e037590.7
  doi: 10.1016/j.genhosppsych.2004.02.006
– volume: 19
  start-page: 327
  year: 2013
  ident: 2025101811301502000_10.4.e037590.40
  article-title: Antenatal depression and its predictors in Lahore, Pakistan
  publication-title: East Mediterr Health J
  doi: 10.26719/2013.19.4.327
– ident: 2025101811301502000_10.4.e037590.30
  doi: 10.1186/1741-7015-8-38
– ident: 2025101811301502000_10.4.e037590.35
  doi: 10.1007/s00737-007-0193-9
– ident: 2025101811301502000_10.4.e037590.39
  doi: 10.1100/2012/840421
– volume: 1
  start-page: e26
  year: 2013
  ident: 2025101811301502000_10.4.e037590.29
  article-title: National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010
  publication-title: Lancet Glob Health
  doi: 10.1016/S2214-109X(13)70006-8
– ident: 2025101811301502000_10.4.e037590.16
– ident: 2025101811301502000_10.4.e037590.19
  doi: 10.1111/j.1469-7610.2006.01714.x
– ident: 2025101811301502000_10.4.e037590.44
  doi: 10.1177/0020764008094645
– ident: 2025101811301502000_10.4.e037590.45
  doi: 10.1016/S0140-6736(10)61508-5
– ident: 2025101811301502000_10.4.e037590.23
  doi: 10.2217/whe.11.96
– volume: 46
  start-page: s45
  year: 2004
  ident: 2025101811301502000_10.4.e037590.34
  article-title: Health services research into postnatal depression: results from a preliminary cross-cultural study
  publication-title: Br J Psychiatry Suppl
  doi: 10.1192/bjp.184.46.s45
– ident: 2025101811301502000_10.4.e037590.15
  doi: 10.1001/archgenpsychiatry.2010.111
– volume: 35
  start-page: 38
  year: 2014
  ident: 2025101811301502000_10.4.e037590.21
  article-title: Meta-Analytic findings of the relation between maternal prenatal stress and anxiety and child cognitive outcome
  publication-title: J Dev Behav Pediatr
  doi: 10.1097/DBP.0000000000000003
– ident: 2025101811301502000_10.4.e037590.38
  doi: 10.1017/S0033291703008286
– volume: 66
  start-page: 22
  year: 2005
  ident: 2025101811301502000_10.4.e037590.26
  article-title: Comorbid anxiety and depression
  publication-title: J Clin Psychiatry
– ident: 2025101811301502000_10.4.e037590.2
  doi: 10.1111/j.1750-8606.2008.00077.x
– volume: 44
  start-page: 2799
  year: 2014
  ident: 2025101811301502000_10.4.e037590.27
  article-title: Second-Trimester maternal distress increases the risk of small for gestational age
  publication-title: Psychol Med
  doi: 10.1017/S0033291714000300
– ident: 2025101811301502000_10.4.e037590.28
  doi: 10.1097/PSY.0b013e31820a62ce
– ident: 2025101811301502000_10.4.e037590.37
  doi: 10.3389/fpsyt.2019.00927
– ident: 2025101811301502000_10.4.e037590.41
– volume: 36
  start-page: 156
  year: 2016
  ident: 2025101811301502000_10.4.e037590.18
  article-title: Preventing infant and child morbidity and mortality due to maternal depression
  publication-title: Best Pract Res Clin Obstet Gynaecol
  doi: 10.1016/j.bpobgyn.2016.05.007
– ident: 2025101811301502000_10.4.e037590.47
  doi: 10.1007/978-1-4899-3242-6
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Snippet IntroductionPrenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an...
Prenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an intervention...
Introduction Prenatal anxiety is a prevalent condition that is harmful for women and a strong predictor of postpartum depression. This trial assesses an...
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StartPage e037590
SubjectTerms Anxiety
Anxiety - therapy
Anxiety disorders
Behavior modification
Birth weight
Clinical Trials, Phase III as Topic
Cognitive Behavioral Therapy
Costs
depression & mood disorders
Economic analysis
Families & family life
Female
Hospitals
Humans
Infant, Newborn
Intervention
Low income groups
Managerial skills
Medical diagnosis
Mental depression
Mental disorders
Mental Health
Mothers
Pakistan
Postpartum depression
Postpartum period
Pregnancy
Pregnancy - psychology
Premature Birth
prenatal diagnosis
Prevention
Qualitative research
Randomized Controlled Trials as Topic
Risk factors
Sex discrimination
Single-Blind Method
Social support
Stress
therapeutics
Womens health
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Title Cognitive–behavioral therapy-based intervention to treat symptoms of anxiety in pregnancy in a prenatal clinic using non-specialist providers in Pakistan: design of a randomised trial
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Volume 10
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