Comparison of standard prophylactic, intermediate prophylactic and therapeutic anticoagulation in patients with severe COVID-19: protocol for the ANTICOVID multicentre, parallel-group, open-label, randomised controlled trial

IntroductionCOVID-19 induces venous, arterial and microvascular thrombosis, involving several pathophysiological processes. In patients with severe COVID-19 without macrovascular thrombosis, escalating into high-dose prophylactic anticoagulation (HD-PA) or therapeutic anticoagulation (TA) could be b...

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Bibliographic Details
Published in:	BMJ open Vol. 12; no. 4; p. e059383
Main Authors:	Labbe, Vincent, Contou, Damien, Heming, Nicholas, Megarbane, Bruno, Ait-Oufella, Hafid, Boissier, Florence, Carreira, Serge, Robert, Alexandre, Vivier, Emmanuel, Fejjal, Mohamed, Doyen, Denis, Monchi, Mehran, Preau, Sebastien, Noel-Savina, Elise, Souweine, Bertrand, Zucman, Noémie, Picos, Santiago Alberto, Dres, Martin, Juguet, William, Mariotte, Eric, Timsit, Jean-François, Turpin, Matthieu, Razazi, Keyvan, Gendreau, Ségolène, Baloul, Samia, Voiriot, Guillaume, Fartoukh, Muriel, Audureau, Etienne, Mekontso Dessap, Armand
Format:	Journal Article
Language:	English
Published:	England British Medical Journal Publishing Group 26.04.2022 BMJ Publishing Group LTD BMJ Publishing Group
Series:	Protocol
Subjects:	Anticoagulants - therapeutic use Anticoagulation Blood Coagulation Cardiology and cardiovascular system Coronaviruses COVID-19 Creatinine Emerging diseases Epidural Human health and pathology Humans Infectious Diseases Ischemia Life Sciences Microcirculation Mortality Multicenter Studies as Topic Patients Pneumonia Pulmonary arteries Pulmonary embolisms Pulmonology and respiratory tract Quality of Life Randomized Controlled Trials as Topic Respiratory infections Severe acute respiratory syndrome coronavirus 2 Thromboembolism Thrombosis Toxicology Veins & arteries COVID-19 Anticoagulation Thromboembolism Respiratory infections
ISSN:	2044-6055, 2044-6055
Online Access:	Get full text
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