Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite instability-high (dMMR/MSI-H) or proficient/stable (MMRp/MSS) endometrial cancer: interim results from GARNET—a phase I, single-arm study
BackgroundDostarlimab is a humanized monoclonal antibody that binds with high affinity to PD-1, resulting in inhibition of binding to PD-L1 and PD-L2. We report interim data from patients with endometrial cancer (EC) participating in a phase I trial of single-agent dostarlimab.MethodsGARNET, an ongo...
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| Veröffentlicht in: | Journal for immunotherapy of cancer Jg. 10; H. 1; S. e003777 |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
England
BMJ Publishing Group Ltd
01.01.2022
BMJ Publishing Group LTD BMJ Publishing Group |
| Schriftenreihe: | Original research |
| Schlagworte: | |
| ISSN: | 2051-1426, 2051-1426 |
| Online-Zugang: | Volltext |
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