Development of a critical appraisal tool to assess the quality of cross-sectional studies (AXIS)

ObjectivesThe aim of this study was to develop a critical appraisal (CA) tool that addressed study design and reporting quality as well as the risk of bias in cross-sectional studies (CSSs). In addition, the aim was to produce a help document to guide the non-expert user through the tool.DesignAn in...

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Veröffentlicht in:BMJ open Jg. 6; H. 12; S. e011458
Hauptverfasser: Downes, Martin J, Brennan, Marnie L, Williams, Hywel C, Dean, Rachel S
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England BMJ Publishing Group LTD 01.12.2016
BMJ Publishing Group
Schlagworte:
Bias
Clinical Decision-Making
Consensus
Cross-Sectional Studies - standards
Delphi Technique
Epidemiology
Evidence Based Practice
Evidence-based medicine
Evidence-Based Medicine - methods
Humans
Quality
Research Design - standards
Studies
Systematic review
Veterinary medicine
Critical appraisal
Delphi
Cross sectional studies
Evidence-based Healthcare
ISSN:2044-6055, 2044-6055
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Zusammenfassung:ObjectivesThe aim of this study was to develop a critical appraisal (CA) tool that addressed study design and reporting quality as well as the risk of bias in cross-sectional studies (CSSs). In addition, the aim was to produce a help document to guide the non-expert user through the tool.DesignAn initial scoping review of the published literature and key epidemiological texts was undertaken prior to the formation of a Delphi panel to establish key components for a CA tool for CSSs. A consensus of 80% was required from the Delphi panel for any component to be included in the final tool.ResultsAn initial list of 39 components was identified through examination of existing resources. An international Delphi panel of 18 medical and veterinary experts was established. After 3 rounds of the Delphi process, the Appraisal tool for Cross-Sectional Studies (AXIS tool) was developed by consensus and consisted of 20 components. A detailed explanatory document was also developed with the tool, giving expanded explanation of each question and providing simple interpretations and examples of the epidemiological concepts being examined in each question to aid non-expert users.ConclusionsCA of the literature is a vital step in evidence synthesis and therefore evidence-based decision-making in a number of different disciplines. The AXIS tool is therefore unique and was developed in a way that it can be used across disciplines to aid the inclusion of CSSs in systematic reviews, guidelines and clinical decision-making.
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MJD, MLB and RSD contributed equally to this work.
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2016-011458