Chitosan in Biomedical Engineering: A Critical Review

Biomedical engineering seeks to enhance the quality of life by developing advanced materials and technologies. Chitosan-based biomaterials have attracted significant attention because of having unique chemical structures with desired biocompatibility and biodegradability, which play different roles...

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Veröffentlicht in:Current stem cell research & therapy Jg. 14; H. 2; S. 93
Hauptverfasser: Mohebbi, Shabnam, Nezhad, Mojtaba Nasiri, Zarrintaj, Payam, Jafari, Seyed Hassan, Gholizadeh, Saman Seyed, Saeb, Mohammad Reza, Mozafari, Masoud
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United Arab Emirates 01.01.2019
Schlagworte:
gene therapy
tissue engineering
Chitosan
biomaterial
stem cell
biomedical engineering
ISSN:2212-3946, 2212-3946
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Zusammenfassung:Biomedical engineering seeks to enhance the quality of life by developing advanced materials and technologies. Chitosan-based biomaterials have attracted significant attention because of having unique chemical structures with desired biocompatibility and biodegradability, which play different roles in membranes, sponges and scaffolds, along with promising biological properties such as biocompatibility, biodegradability and non-toxicity. Therefore, chitosan derivatives have been widely used in a vast variety of uses, chiefly pharmaceuticals and biomedical engineering. It is attempted here to draw a comprehensive overview of chitosan emerging applications in medicine, tissue engineering, drug delivery, gene therapy, cancer therapy, ophthalmology, dentistry, bio-imaging, bio-sensing and diagnosis. The use of Stem Cells (SCs) has given an interesting feature to the use of chitosan so that regenerative medicine and therapeutic methods have benefited from chitosan-based platforms. Plenty of the most recent discussions with stimulating ideas in this field are covered that could hopefully serve as hints for more developed works in biomedical engineering.
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ISSN:2212-3946
2212-3946
DOI:10.2174/1574888X13666180912142028