Sex determination in mammalian germ cells: extrinsic versus intrinsic factors

Mammalian germ cells do not determine their sexual fate based on their XX or XY chromosomal constitution. Instead, sexual fate is dependent on the gonadal environment in which they develop. In a fetal testis, germ cells commit to the spermatogenic programme of development during fetal life, although...

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Bibliographic Details
Published in:	Reproduction (Cambridge, England) Vol. 139; no. 6; p. 943
Main Authors:	Bowles, Josephine, Koopman, Peter
Format:	Journal Article
Language:	English
Published:	England 01.06.2010
Subjects:	Animals Cell Movement Epigenesis, Genetic Female Fetal Development Germ Cells - cytology Intracellular Signaling Peptides and Proteins - physiology Male Meiosis Oocytes - cytology Oogenesis - physiology Ovary - cytology Ovary - embryology Pluripotent Stem Cells Sex Determination Processes Signal Transduction Spermatogenesis - physiology Spermatozoa - cytology Testis - cytology Testis - embryology Tretinoin - physiology
ISSN:	1741-7899, 1741-7899
Online Access:	Get more information
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