Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival

BackgroundThe composition of the tumor immune microenvironment (TIME) associated with good prognosis generally also predicts the success of immunotherapy, and both entail the presence of pre-existing tumor-specific T cells. Here, the blueprint of the TIME associated with such an ongoing tumor-specif...

Full description

Saved in:

Bibliographic Details
Published in:	Journal for immunotherapy of cancer Vol. 10; no. 2; p. e004346
Main Authors:	Abdulrahman, Ziena, Santegoets, Saskia J, Sturm, Gregor, Charoentong, Pornpimol, Ijsselsteijn, Marieke E, Somarakis, Antonios, Höllt, Thomas, Finotello, Francesca, Trajanoski, Zlatko, van Egmond, Sylvia L, Mustafa, Dana A M, Welters, Marij J P, de Miranda, Noel F C C, van der Burg, Sjoerd H
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group Ltd 01.02.2022 BMJ Publishing Group LTD BMJ Publishing Group
Series:	Original research
Subjects:	Antigens Basic Tumor Immunology Cancer Cancer therapies Chemokines - metabolism Cytokines Female Gene expression Head & neck cancer Human papillomavirus Humans Immunotherapy Lymphocytes Male Medical prognosis Monitoring, Immunologic - methods Patients Quality control Software Squamous cell carcinoma Surgery T-Lymphocytes - metabolism Throat cancer tumor microenvironment Tumor Microenvironment - immunology Tumor necrosis factor-TNF Tumors United States > US Netherlands Germany immunotherapy tumor microenvironment
ISSN:	2051-1426, 2051-1426
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!