Mirror movements in parkinsonism: evaluation of a new clinical sign

Background: Mirror movements (MM) are not widely appreciated in parkinsonism and no report has evaluated this clinical sign in detail. Objectives: To define the parkinsonian clinical features associated with MM in patients with early, asymmetric parkinsonism. Methods: Twenty seven patients with earl...

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Vydáno v:	Journal of neurology, neurosurgery and psychiatry Ročník 76; číslo 10; s. 1355 - 1359
Hlavní autoři:	Espay, A J, Li, J-Y, Johnston, L, Chen, R, Lang, A E
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England BMJ Publishing Group Ltd 01.10.2005 BMJ Publishing Group LTD BMJ Group
Témata:	Adult Aged Aged, 80 and over Asymmetry Cerebrovascular Circulation - physiology Dopamine Female Foot - physiopathology Functional Laterality - physiology Humans LAA LAL lateralised Unified Parkinson’s Disease Rating Scale least affected arm least affected leg MAA MAL Male Middle Aged mirror movements most affected arm most affected leg Motor Cortex - blood supply Parkinson Disease - diagnosis Parkinson Disease - epidemiology Parkinson Disease - physiopathology Parkinson's disease Phenomenology Severity of Illness Index Synkinesis - diagnosis Synkinesis - epidemiology Synkinesis - physiopathology Unified Parkinson’s Disease Rating Scale UPDRS Videotape Recording
ISSN:	0022-3050, 1468-330X
On-line přístup:	Získat plný text
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Popis
Shrnutí:	Background: Mirror movements (MM) are not widely appreciated in parkinsonism and no report has evaluated this clinical sign in detail. Objectives: To define the parkinsonian clinical features associated with MM in patients with early, asymmetric parkinsonism. Methods: Twenty seven patients with early Parkinson’s disease were evaluated using a standardised videotaping protocol. MM were scored from blinded video assessment using a clinical scale that rates the amplitude, distribution, and proportion of mirroring in the less affected limb. Parkinsonian features were combined into axial and lateralised scores using related items of the Unified Parkinson’s Disease Rating Scale. Results: MM were present in 24 of 27 patients. There was a significant linear correlation between the degree of asymmetry of motor deficits and MM on the less affected side. The effect of asymmetry was greater when the proportional rather than the absolute motor difference between sides was largest. Asymmetry in leg rigidity was the most important examination feature in the prediction of contralateral foot mirroring. Conclusions: MM are a clinical feature of the unaffected or less affected side in mild asymmetric parkinsonism. Their presence may be a useful clinical finding in early parkinsonism.
Bibliografie:	ark:/67375/NVC-BHJ0JF03-6 local:0761355 istex:D13E43184BAD9EB6EDA9C6298522EEE01DB2C703 Correspondence to:  Dr A E Lang  Toronto Western Hospital, Division of Neurology, 399 Bathurst Street, MC 7-413, Toronto, Ontario M5T 2S8, Canada; lang@uhnres.utoronto.ca PMID:16170075 href:jnnp-76-1355.pdf ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23
ISSN:	0022-3050 1468-330X
DOI:	10.1136/jnnp.2005.062950