Association between bacterial homoplastic variants and radiological pathology in tuberculosis

BackgroundUnderstanding how pathogen genetic factors contribute to pathology in TB could enable tailored treatments to the most pathogenic and infectious strains. New strategies are needed to control drug-resistant TB, which requires longer and costlier treatment. We hypothesised that the severity o...

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Bibliographic Details
Published in:	Thorax Vol. 75; no. 7; pp. 584 - 591
Main Authors:	Grandjean, Louis, Monteserin, Joha, Gilman, Robert, Pauschardt, Julia, Rokadiya, Sakib, Bonilla, Cesar, Ritacco, Viviana, Vidal, Julia Rios, Parkhill, Julian, Peacock, Sharon, Moore, David AJ, Balloux, Francois
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group Ltd and British Thoracic Society 01.07.2020 BMJ Publishing Group LTD BMJ Publishing Group
Series:	Original research
Subjects:	Adolescent Adult Aged Bacterial Proteins - genetics Bacterial Proteins - metabolism Child clinical epidemiology Confounding (Statistics) Disease prevention DNA, Bacterial - genetics Drug resistance Female Follow-Up Studies Genomes Genotype Humans imaging/CT MRI etc Laboratory animals Male Microbial Sensitivity Tests Middle Aged Mutation Mycobacterium tuberculosis - genetics Pathogens Pathology Phylogenetics Radiology Retrospective Studies Tuberculosis Tuberculosis, Multidrug-Resistant - genetics Tuberculosis, Multidrug-Resistant - metabolism Tuberculosis, Multidrug-Resistant - microbiology Variables Whole genome sequencing Young Adult imaging/CT MRI etc clinical epidemiology tuberculosis
ISSN:	0040-6376, 1468-3296, 1468-3296
Online Access:	Get full text
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