Mathematical Modeling of Cell Adhesion in Shear Flow: Application to Targeted Drug Delivery in Inflammation and Cancer Metastasis

Cell adhesion plays a pivotal role in diverse biological processes that occur in the dynamic setting of the vasculature, including inflammation and cancer metastasis. Although complex, the naturally occurring processes that have evolved to allow for cell adhesion in the vasculature can be exploited...

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Bibliographic Details

Published in:	Current pharmaceutical design Vol. 13; no. 15; pp. 1511 - 1526
Main Authors:	Jadhav, Sameer, Eggleton, Charles, Konstantopoulos, Konstantinos
Format:	Journal Article
Language:	English
Published:	United Arab Emirates Bentham Science Publishers Ltd 01.05.2007
Subjects:	Animals Blood Circulation Cell Adhesion Cell Aggregation Cell Communication Cell Movement Drug Delivery Systems Humans Inflammation - drug therapy Mathematics Models, Theoretical Neoplasm Metastasis - drug therapy Selectins - analysis Selectins - physiology Shear Strength
ISSN:	1381-6128, 1873-4286, 1873-4286
Online Access:	Get full text
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