Mathematical Modeling of Cell Adhesion in Shear Flow: Application to Targeted Drug Delivery in Inflammation and Cancer Metastasis

Cell adhesion plays a pivotal role in diverse biological processes that occur in the dynamic setting of the vasculature, including inflammation and cancer metastasis. Although complex, the naturally occurring processes that have evolved to allow for cell adhesion in the vasculature can be exploited...

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Vydáno v:	Current pharmaceutical design Ročník 13; číslo 15; s. 1511 - 1526
Hlavní autoři:	Jadhav, Sameer, Eggleton, Charles, Konstantopoulos, Konstantinos
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United Arab Emirates Bentham Science Publishers Ltd 01.05.2007
Témata:	Animals Blood Circulation Cell Adhesion Cell Aggregation Cell Communication Cell Movement Drug Delivery Systems Humans Inflammation - drug therapy Mathematics Models, Theoretical Neoplasm Metastasis - drug therapy Selectins - analysis Selectins - physiology Shear Strength
ISSN:	1381-6128, 1873-4286, 1873-4286
On-line přístup:	Získat plný text
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