Development and validation of risk prediction algorithms to estimate future risk of common cancers in men and women: prospective cohort study

Objective To derive and validate a set of clinical risk prediction algorithm to estimate the 10-year risk of 11 common cancers. Design Prospective open cohort study using routinely collected data from 753 QResearch general practices in England. We used 565 practices to develop the scores and 188 for...

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Bibliographic Details
Published in:	BMJ open Vol. 5; no. 3; p. e007825
Main Authors:	Hippisley-Cox, Julia, Coupland, Carol
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group LTD 17.03.2015 BMJ Publishing Group
Subjects:	Adult Age Factors Aged Aged, 80 and over Alcohol Drinking - epidemiology Alcohol use Algorithms Antipsychotic Agents - therapeutic use Bipolar Disorder - epidemiology Body Mass Index Breast cancer Chronic illnesses Codes Comorbidity Contraceptives, Oral - therapeutic use Diabetes Diabetes Mellitus, Type 1 - epidemiology Diabetes Mellitus, Type 2 - epidemiology Disease Electronic health records England - epidemiology Epidemiology Family medical history Female Forecasting - methods Gynecology Hormone Replacement Therapy Hospitals Humans Incidence Male Medical diagnosis Medical research Middle Aged Mortality Neoplasms - epidemiology Neoplasms - ethnology Neoplasms - genetics Neoplasms, Second Primary - epidemiology Ovarian cancer Patient admissions Population Poverty Primary care Proportional Hazards Models Prospective Studies Risk Assessment - methods Risk factors ROC Curve Schizophrenia - epidemiology Smoking Smoking - epidemiology Ulcers Womens health England United Kingdom > UK cancer PRIMARY CARE QResearch
ISSN:	2044-6055, 2044-6055
Online Access:	Get full text
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