RNA Hypomethylation and Unchanged DNA Methylation Levels in the Cortex of ApoE4 Carriers and Alzheimer's Disease Subjects

Alzheimer's disease (AD) is a progressive neurodegenerative disorder, and ApoE4 variants are significant risk factors for AD. Epigenetic modifications are involved in AD pathology. However, it is unclear whether DNA/RNA methylation plays a role in AD pathology, and dysregulation of DNA/RNA meth...

Full description

Bibliographic Details

Published in:	Current Alzheimer research Vol. 19; no. 7; p. 530
Main Authors:	Shen, Wei-Bin, Yang, James Jiao, Yang, Peixin
Format:	Journal Article
Language:	English
Published:	United Arab Emirates 01.01.2022
Subjects:	Alzheimer Disease - metabolism Apolipoprotein E4 - genetics Apolipoprotein E4 - metabolism DNA Methylation Humans Methyltransferases - genetics Methyltransferases - metabolism RNA - metabolism DNA methylation methyltransferases Alzheimer’s disease demethylase RNA methylation ApoE4
ISSN:	1875-5828, 1875-5828
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!