Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT

The tall cell (TC) variant of papillary thyroid carcinoma (PTC) has an unfavorable prognosis. The diagnostic criteria remain inconsistent, and the role of a minor TC component is unclear. Molecular diagnostic markers are not available; however, there are two potential candidates: BRAF V600E and telo...

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Veröffentlicht in:	Endocrine-related cancer Jg. 22; H. 3; S. 419 - 429
Hauptverfasser:	Dettmer, Matthias S, Schmitt, Anja, Steinert, Hans, Capper, David, Moch, Holger, Komminoth, Paul, Perren, Aurel
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.06.2015
Schlagworte:	Carcinoma - enzymology Carcinoma - genetics Carcinoma - pathology Carcinoma, Papillary Female Humans Male Middle Aged Mutation Prognosis Proto-Oncogene Proteins B-raf - genetics Telomerase - genetics Thyroid Cancer, Papillary Thyroid Neoplasms - enzymology Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Treatment Outcome diagnostic criteria BRAF TERT papillary thyroid carcinoma prognosis tall cell
ISSN:	1479-6821
Online-Zugang:	Weitere Angaben
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