Evidence for decreasing sperm count in African population from 1965 to 2015

Purpose: This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African...

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Veröffentlicht in:African health sciences Jg. 17; H. 2; S. 418 - 427
Hauptverfasser: Sengupta, Pallav, Nwagha, Uchenna, Dutta, Sulagna, Krajewska-Kulak, Elzbieta, Izuka, Emmanuel
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Uganda Makerere University Medical School 01.06.2017
Makerere Medical School
Schlagworte:
Adult
Africa
Africa - epidemiology
Body fluids
Humans
Male
Mental health
Middle Aged
Reproductive health
Research methodology
Risk Factors
Semen quality
sperm concentration
sperm count
Sperm Count - statistics & numerical data
Young Adult
Semen quality
sperm concentration
sperm count
ISSN:1680-6905, 1729-0503, 1680-6905, 1729-0503
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Zusammenfassung:Purpose: This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African population between 1965 and 2015. Methods: In the course of retrieval of data following MOOSE guidelines and PRISMA checklist, we found a total of fourteen studies that have been conducted during that period on altering sperm concentration in the African male. Results: Following analysis of the data, a time-dependent decline of sperm concentration (r = -0.597, p = 0.02) and an overall 72.6% decrease in mean sperm concentration was noted in the past 50 years. The major matter of concern is the present mean concentration (20.38×106/ml) is very near to WHO cut-off value of 2010 of 15×106/ml. Several epidemic diseases, genital tract infection, pesticides and heavy metal toxicity, regular consumption of tobacco and alcohol are reported as predominant causative factors. Conclusion: This comprehensive, evidence-based meta-analysis and systematic review concisely presents the evidence of decreased sperm concentration in the African male over past 50 years with possible causative factors to serve the scientific research zone related to male reproductive health.
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ISSN:1680-6905
1729-0503
1680-6905
1729-0503
DOI:10.4314/ahs.v17i2.16